Trial reportInternational journal of general medicine2021
The Application of Electrical Impedance Tomography During the Ventilator Weaning Process.
Trial report in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05904652 (A Randomised, Feasibility Trial of Simultaneous Application of Flow at Extubation), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomised, Feasibility Trial of Simultaneous Application of Flow at Extubation (SAFEx) in Patients Requiring Intubation and Ventilation for the Management of Acute Respiratory Failure
Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Liberation from Mechanical Ventilation in Acute Hypoxemic Respiratory Failure or Adult Respiratory Distress Syndrome: A Review.Journal of clinical medicine · 2026Review
- Pre-SAFEx: protocol for a single-centre, randomised, unblinded feasibility trial of Simultaneous Application of Flow at Extubation (SAFEx) in patients requiring intubation and ventilation for the management of acute respiratory failure.Pilot and feasibility studies · 2026Article
- Recommendations for lung ventilation and perfusion assessment with chest electrical impedance tomography in critically ill adult patients: an international evidence-based and expert Delphi consensus study.EClinicalMedicine · 2025Article
- Lung electrical impedance tomography during positioning, weaning and chest physiotherapy in mechanically ventilated critically ill patients: a narrative review.Annals of intensive care · 2025Review
- Ventilation distribution during spontaneous breathing trials predicts liberation from mechanical ventilation: the VISION study.Critical care (London, England) · 2025Article
- Three-Dimensional Electrical Impedance Imaging During Spontaneous Breathing Trials in Patients With Acute Hypoxic Respiratory Failure: A Pilot Study.Critical care explorations · 2025Article
- Predictors of weaning failure in ventilated intensive care patients: a systematic evidence map.Critical care (London, England) · 2024Review
- Expert opinion document: "Electrical impedance tomography: applications from the intensive care unit and beyond".Journal of anesthesia, analgesia and critical care · 2022Review
- Roles of electrical impedance tomography in lung transplantation.Frontiers in physiology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study proposes the investigation of electrical impedance tomography (EIT) as a useful predictor for ventilator weaning.
methodsThe study design was a nested case-control study and patients who were admitted to the intensive care unit and underwent their first tracheal intubation were enrolled. Those who successfully completed ventilator weaning and extubation after the first spontaneous breathing trial (SBT) were included in the weaning success group, while those who did not pass the SBT or received secondary intubation within 48 hours were included in the weaning failure group. In both groups, EIT was adopted to record the monitoring data in three phases: before the SBT (pre-SBT), during the SBT (SBT), and after the SBT (post-SBT).
resultsA total of 53 patients were enrolled, including 41 cases in the weaning success group and 12 cases in the weaning failure group. The logistic regression analysis showed that the pre-SBT global impedance (GI) and the SBT region of interest 2 (ROI2) were significantly higher in the weaning success group than in the weaning failure group (p = 0.0001 and p = 0.002). The pre-SBT GI predicted weaning success with a sensitivity of 0.524, a specificity of 0.818, a p-value of 0.0496, and a 95% confidence interval (CI) of 0.001-0.978. The sensitivity, specificity, p-value, and 95% CI for the SBT ROI2 were 1, 0.595, 0.0164, and 1.010-1.108, respectively.
conclusionFor patients without contraindications to EIT, the application of EIT is recommended to be added to the existing evaluation system for ventilator weaning, as it could help improve the weaning success rate. Further cohort studies are needed to investigate the actual efficacy of EIT after it has been added to the evaluation system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.