Evidence map›Paper›PMID 34703290›Full record

ArticleInternational journal of general medicine2021

Hip Replacement in Ankylosing Spondylitis Patients with Advanced Hip Involvement: Factors Associated with Bilateral Total Hip Arthroplasty.

Liangliang Li, Jun Fu, Chi Xu, Ming Ni, Wei Chai, Libo Hao, Yonggang Zhou, Jiying Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Liangliang LiMedical School of Chinese PLA, Beijing, People's Republic of China.
Jun FuDepartment of Orthopedics, The First Medical Centre, Chinese PLA General Hospital, Beijing, People's Republic of China.
Chi XuDepartment of Orthopedics, The First Medical Centre, Chinese PLA General Hospital, Beijing, People's Republic of China.ORCID 0000-0003-4211-0657
Ming NiDepartment of Orthopedics, The First Medical Centre, Chinese PLA General Hospital, Beijing, People's Republic of China.
Wei ChaiDepartment of Orthopedics, The First Medical Centre, Chinese PLA General Hospital, Beijing, People's Republic of China.
Libo HaoDepartment of Orthopedics, The First Medical Centre, Chinese PLA General Hospital, Beijing, People's Republic of China.
Yonggang ZhouDepartment of Orthopedics, The First Medical Centre, Chinese PLA General Hospital, Beijing, People's Republic of China.
Jiying ChenDepartment of Orthopedics, The First Medical Centre, Chinese PLA General Hospital, Beijing, People's Republic of China.
Chinese PLA General Hospital · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to compare the clinical data of ankylosing spondylitis (AS) patients who underwent unilateral and bilateral total hip arthroplasty (THA) due to advanced hip involvement. Furthermore, to determine the factors associated with bilateral THA.

methodsUtilizing a single-institution database, we selected 373 consecutive AS patients undergoing primary THA from 2012 to 2017 and compared the clinical characteristics and anti-tumor necrosis factor (TNF) therapy of the patients who underwent unilateral and bilateral THA. Logistic regression was used to identify factors associated with bilateral THA.

resultsBilateral THA was performed in 67.3% (n=251) of the patients. Male patients had a higher frequency of undergoing bilateral THA compared with female ones (P<0.05). The proportion of the patients who had bilateral onset in hips, administration of TNF inhibitors, flexion contracture in the hip, and a BASRI-hip score of 4 was significantly higher in patients with bilateral THA than that with unilateral THA (P<0.05). Patients with bilateral THA experienced longer disease duration than those with unilateral THA (P<0.05). The results of the logistic regression showed that factors related to bilateral THA were bilateral onset in hips, administration of TNF inhibitors, a BASRI-hip score of 4, and an erythrocyte sedimentation rate (ESR) level (P<0.05).

conclusionBilateral THA is more common in AS patients with advanced hip involvement. Bilateral onset in hips, a BASRI-hip score of 4, and a higher level of ESR are risk factors associated with bilateral THA, while anti-TNF therapy is a protective factor reducing the progression of hip involvement to bilateral THA.

Indexed as

ankylosing spondylitisanti-TNF therapybilateral total hip arthroplastyhip involvement

Identifiers

PMID34703290
PMCPMC8526512
OpenAlexW3205692309

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.