Evidence map›Paper›PMID 34703218›Full record

ArticleClinical interventions in aging2021

Predictors of Adverse Events Among Chronic Total Occlusion Patients Undergoing Successful Percutaneous Coronary Intervention and Medical Therapy.

Le Yang, Lei Guo, Haichen Lv, Xiaodong Liu, Lei Zhong, Huaiyu Ding, Xuchen Zhou, Hao Zhu, Rongchong Huang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07020858 (The Value of FAPI Imaging for the Prediction of Adverse Cardiovascular Events in Chronic Total Occlusion of Coronary Artery Disease), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07020858 recruitingnot on this mapstarted 2025, after this paper: background citation

The Value of FAPI Imaging for the Prediction of Adverse Cardiovascular Events in Chronic Total Occlusion of Coronary Artery Disease (FACT-2 Trial)

Typeobservational_patient_registrySponsorLin ZhaoRan2025 to 2027Enrolled470ConditionsChronic Total Occlusion (CTO), Chronic Coronary SyndromeArmsFAPl lmaging
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Predictors of long-term adverse outcomes after successful chronic total occlusion intervention: physiology or morphology?Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Le YangDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian City, People's Republic of China.
Lei Guo *Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian City, People's Republic of China.ORCID 0000-0003-3698-6986
Haichen LvDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian City, People's Republic of China.ORCID 0000-0002-7369-5750
Xiaodong LiuDepartment of Radiology, Dalian Friendship Hospital, Dalian City, People's Republic of China.
Lei ZhongDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian City, People's Republic of China.
Huaiyu DingDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian City, People's Republic of China.
Xuchen ZhouDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian City, People's Republic of China.
Hao ZhuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian City, People's Republic of China.
Rongchong Huang *Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian City, People's Republic of China.ORCID 0000-0002-2607-2112
Dalian Medical University · CNCapital Medical University · CNThe Third People's Hospital of Dalian City · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLimited data are available on the predictors of major adverse cardiac events (MACE) after a successful coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI) and medical therapy. This study aimed to identify predictors of MACE in CTO patients undergoing successful recanalization and medical therapy.

methodsA total of 2015 patients with CTOs were enrolled. About 718 patients underwent successful CTO recanalization, and 1297 patients received medical therapy. The primary outcome was the frequency of MACE, defined as a composite of cardiac death, myocardial infarction, and target-vessel revascularization. Multivariate models were used to determine predictors of MACE.

resultsIn successful CTO recanalization group, MACE occurred in 123 (17.1%) patients. In multivariate analysis, heart failure (hazard ratio [HR] 1.77, 95% confidence interval [CI]: 1.04-3.04,

conclusionHeart failure was predictor for composite cardiovascular events in patients with CTO after successful recanalization. Male gender, diabetes mellitus, heart failure, J-CTO score and multivessel disease were predictors of MACE in CTO patients with medical therapy.

Indexed as

Coronary OcclusionHeart FailureMyocardial InfarctionPercutaneous Coronary InterventionChronic DiseaseCoronary AngiographyHumansMaleRisk FactorsTreatment Outcomecoronary chronic total occlusionsMACEmedical therapypercutaneous coronary interventionpredictors

Identifiers

PMID34703218
PMCPMC8523319
OpenAlexW3206060005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.