Evidence map›Paper›PMID 34703152›Full record

ArticleJournal of global infectious diseases

Economic Evaluation of Implementing a Rapid Point-of-Care Screening Test for the Identification of Hepatitis C Virus under National Viral Hepatitis Control Programme in Tamil Nadu, South India.

Muniyandi Malaisamy, Karikalan Nagarajan, Tyagi Kirti, Singh Malkeet, Prakash Venkatesan, S Senthilkumar, Karthikeyan Sananthya, Krishnan Rajendran, Rajsekar Kavitha, Shanmugam Vivekanandan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of global infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Muniyandi MalaisamyDepartment of Health Economics, ICMR-National Institute for Research in Tuberculosis, New Delhi, India.
Karikalan NagarajanDepartment of Health Economics, ICMR-National Institute for Research in Tuberculosis, New Delhi, India.
Tyagi KirtiDepartment of Health Research, Ministry of Health and Family Welfare, New Delhi, India.
Singh MalkeetDepartment of Health Research, Ministry of Health and Family Welfare, New Delhi, India.
Prakash VenkatesanDepartment of Public Health and Preventive Medicine, Directorate of Medical and Rural Health Services, Government of Tamil Nadu, Chennai, Tamil Nadu, India.
S SenthilkumarDepartment of Health Economics, ICMR-National Institute for Research in Tuberculosis, New Delhi, India.
Karthikeyan SananthyaDepartment of Health Economics, ICMR-National Institute for Research in Tuberculosis, New Delhi, India.
Krishnan RajendranDepartment of Statistics, ICMR-National Institute for Research in Tuberculosis, New Delhi, India.
Rajsekar KavithaDepartment of Health Research, Ministry of Health and Family Welfare, New Delhi, India.
Shanmugam VivekanandanChennai Liver Foundation, Chennai, Tamil Nadu, India.
T S SelvavinayagamDepartment of Public Health and Preventive Medicine, Directorate of Medical and Rural Health Services, Government of Tamil Nadu, Chennai, Tamil Nadu, India.
National Institute of Research in Tuberculosis · INMinistry of Health and Family Welfare · INDepartment of Public · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionViral hepatitis is a crucial public health problem in India. Hepatitis C virus (HCV) elimination is a national priority and a key strategy has been adopted to strengthen the HCV diagnostics services to ensure early and accurate diagnosis.

methodsTo conduct an economic evaluation of implementing a rapid point-of-care screening test for the identification of HCV among the selected key population under the National Viral Hepatitis Control Programme in Tamil Nadu, South India. Economic evaluation of a point-of-care screening test for HCV diagnosis among the key population attending the primary health care centers. A combination of decision tree and Markov model was developed to estimate cost-effectiveness of point-of-care screening test for HCV diagnosis at the primary health care centers. Total costs, quality-adjusted life years (QALYs) of the intervention and comparator, and incremental cost-effectiveness ratio (ICER) were calculated. The model parameter uncertainties which would influence the cost-effectiveness outcome has been evaluated by one-way sensitivity analysis and probabilistic sensitivity analysis.

resultsWhen compared to the tertiary level diagnostic strategy for HCV, the point-of-care screening for selected key population at primary health care level results in a gain of 57 undiscounted QALYs and 38 discounted QALYs, four undiscounted life years and two discounted life years. The negative ICER of the new strategy indicates that it is less expensive and more effective compared with the current HCV diagnosis strategy.

conclusionsThe proposed strategy for HCV diagnosis in the selected key population in Tamil Nadu is dominant and cost-saving compared to the current strategy.

Indexed as

Cost-effectivenessdiagnosiseconomic evaluationhepatitis CIndiakey populationpoint-of-carescreening

Identifiers

PMID34703152
PMCPMC8491813
OpenAlexW3198537474

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.