ArticleJournal of oral and maxillofacial pathology : JOMFP
Erosive oral lichen planus inflicts higher cellular stress than reticular type.
Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Comparison of the effect of the pulsed Er: YAG laser and topical corticosteroid on erosive oral lichen planus: a randomized clinical controlled trial.Lasers in medical science · 2025Trial
- Article
- Serum Catestatin Level as a Novel Biomarker of Oral Lichen Planus.Medical sciences (Basel, Switzerland) · 2026Article
- Oxidative stress and metabolic dysfunction in oral lichen planus pathogenesis.Animal cells and systems · 2026Review
- Inflammatory Markers and Dyslipidemia in Patients with Oral Lichen Planus: A Case-Control Study.Diagnostics (Basel, Switzerland) · 2025Article
- Impact of diabetes mellitus on patients affected by oral lichen planus: a retrospective study.Frontiers in oral health · 2025Article
- DAPK-1 as a Potential Early Marker for Malignant Transformation Risk of Oral Lichen Planus.Cureus · 2024Article
- Potential role of salivary lactic acid bacteria in pathogenesis of oral lichen planus.BMC microbiology · 2024Article
- Microbial Profiles in Oral Lichen Planus: Comparisons with Healthy Controls and Erosive vs. Non-Erosive Subtypes.Diagnostics (Basel, Switzerland) · 2024Article
- Association between oral lichen planus and Candida albicans infection: a systematic review and meta-analysis.American journal of translational research · 2024Review
- Alterations of oral microbiome and metabolic signatures and their interaction in oral lichen planus.Journal of oral microbiology · 2024Article
- Unveiling the Potential of Serum MiR-483-5p: A Promising Diagnostic and Prognostic Biomarker in OLP and OSCC Patients byCurrent pharmaceutical design · 2024Article
- Non-Coding RNAs as Potential Targets for Diagnosis and Treatment of Oral Lichen Planus: A Narrative Review.Biomolecules · 2023Review
- Immunohistochemical expression of T-cell subsets (CD4 and CD8) in oral lichen planus.The Pan African medical journal · 2023Article
- Demographics, Clinicopathological Profile of Oral Lichen Planus of South Kerala Population: A Cross-Sectional Study.Cureus · 2022Article
- Assessment of salivary malondialdehyde level as oxidative stress marker in oral lichen planus and its correlation with psychological stress.Journal of oral and maxillofacial pathology : JOMFPArticle
- Expression of Oestrogen Receptor Alpha (ERα) in Oral Lichen Planus - A Precancerous Inflammatory Disease in Middle-Aged Females.Indian journal of dermatologyArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLichen planus is a chronic inflammatory mucocutaneous disease which frequently involves the oral mucosa. The most common types of oral lichen planus (OLP) are reticular (asymptomatic) and erosive (ulcerative) with malignant potentiality. The aims of the present study are to assess the cellular stress level in both types of OLP lesions with respect to oxidative stress, DNA damage and inflammation. MATERIALS AND
methodsFreshly diagnosed untreated 25 OLP reticular type and 25 OLP erosive (OLP-E) type patients aged 35-55 years were enrolled in the study along with age and sex-matched 25 healthy subjects as control. Tissue antioxidant enzymes were measured biochemically, single-cell DNA damage was measured by comet assay and the molecular markers for inflammation were assessed by using semi-quantitative reverse transcriptase-polymerase chain reaction. Statistical analyses were performed using one-way ANOVA and Tukey's
resultsOxidative stress was significantly greater in OLP-E type compared to the reticular. mRNA expression of cyclooxygenase-2 was significantly elevated (
conclusionsThe unhandled free radicals may imbalance the homeostatic network toward pro-inflammatory, DNA damaging responses, creating a vicious cell-damaging spree resulting in stress. Molecular analyses showed that erosive lichen planus is more under stress than the reticular form.
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