Evidence map›Paper›PMID 34703121›Full record

ArticleJournal of oral and maxillofacial pathology : JOMFP

Histopathologic and immunohistochemical findings of odontogenic jaw cysts treated by decompression technique.

Syed Mustansir-Ul-Hassnain, Vidyadevi Chandavarkar, Mithilesh Narayan Mishra, Pavan Manohar Patil, Deepak Bhargava, Ritika Sharma

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06536907 (The Effect of Decompression on Histologic Diagnoses of Cystic Jaw Lesions), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06536907 completednot on this map

The Effect of Decompression on Histologic Diagnoses of Cystic Jaw Lesions

TypeobservationalSponsorAkdeniz UniversityRan2015 to 2023Enrolled39ConditionsOdontogenic Cysts, Keratocysts of the Jaw, Cysts Dental, Pathology
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Brazilian dental journal
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Syed Mustansir-Ul-HassnainDepartment of Health and Family Welfare, Primary Health Centre, Chuchot, UT of Ladakh, India.
Vidyadevi ChandavarkarDepartment of Oral and Maxillofacial Pathology and Oral Microbiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Mithilesh Narayan MishraDepartment of Oral and Maxillofacial Pathology and Oral Microbiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Pavan Manohar PatilDepartment of Oral and Maxillofacial Surgery, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Deepak BhargavaDepartment of Oral and Maxillofacial Pathology and Oral Microbiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Ritika SharmaDepartment of Oral and Maxillofacial Pathology and Oral Microbiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.
Sharda University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextOdontogenic cysts are among the most common lesions to affect the oral and maxillofacial region. Cysts are capable of causing significant bony disfigurement, tooth displacement and pathological fractures. Several surgical approaches exist for the management of larger cysts of the jaws. These include enucleation, marsupialization and decompression.

aims1. Analysis of histopathologic findings in odontogenic cysts before and after decompression2. Analysis of Ki-67 expression in odontogenic jaw cysts before and after decompression. SETTINGS AND

designDecompression technique was used for the treatment of 10 cases of odontogenic cysts in the study. Incisional biopsies of cystic lining (pretreatment) and corresponding excisional biopsies (posttreatment) were received for histopathologic and immunohistochemical examination. SUBJECTS AND

methodsHematoxylin and eosin stain was used for histopathologic findings, and Ki-67 was used for immunohistochemical findings using antibody Ki-67 in fresh tissue samples.

resultsOverall, radicular cysts, dentigerous cysts, and sialo-odontogenic cyst contained fewer Ki-67

conclusionsThe proliferative activity evaluated by Ki-67 marker was greater in predecompression epithelial lining compared to postdecompression. Our study infers that proliferative rate of the cystic epithelial lining is significantly diminished after decompression.

Indexed as

DecompressionKi-67odontogenic cysts

Identifiers

PMID34703121
PMCPMC8491353
OpenAlexW3196697120

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.