Evidence map›Paper›PMID 34703076›Full record

ArticleJournal of computational and applied mathematics2020

Simulation of blood flow in a sudden expansion channel and a coronary artery.

Wei-Tao Wu, Nadine Aubry, James F Antaki, Mehrdad Massoudi

Abstract read
In one paragraph

Article in Journal of computational and applied mathematics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wei-Tao WuSchool of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing, J.S., 210094, China.
Nadine AubryDepartment of Mechanical Engineering, Tufts University, Medford, MA, 02155, USA.
James F AntakiNancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Mehrdad MassoudiU. S. Department of Energy, National Energy Technology Laboratory (NETL), Pittsburgh, PA, 15236, USA.

Funding

Multiscale Model of Thrombosis in Artificial CirculationR01HL089456 · NHLBI · CORNELL UNIVERSITY · PI ANTAKI, JAMES F., BUTCHER, JONATHAN TALBOT · 2009 to 2024
$8.5M
NHLBI NIH HHS R01 HL089456
6 · The paper itself

Abstract

In this paper, we numerically simulate the flow of blood in two benchmark problems: the flow in a sudden expansion channel and the flow through an idealized curved coronary artery with pulsatile inlet velocity. Blood is modeled as a suspension (a non-linear complex fluid) and the movement of the red blood cell (RBCs) is modeled by using a concentration flux equation. The viscosity of blood is obtained from experimental data. In the sudden expansion flow, the predicted velocity profiles for two different Reynolds numbers (based on the inlet velocity) agree well with the available experiments; furthermore, the numerical results also show that after the sudden expansion there exists a RBCs depletion region. For the second problem, the idealized curved coronary artery, it is found that the RBCs move towards and concentrate near the inner surface where the viscosity is higher and the shear stress lower; this phenomenon may be related to the atherosclerotic plaque formation which usually occurs on the inside surface of the arteries.

Indexed as

Blood flowCoronary arteryNon-linear fluidShear-thinning fluidSuspension

Identifiers

PMID34703076
PMCPMC8545272

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.