Evidence map›Paper›PMID 34703026›Full record

ArticleMolecular psychiatry2022

Medical conditions and Attention-Deficit/Hyperactivity Disorder symptoms from early childhood to adolescence.

Cédric Galéra, Samuele Cortese, Massimiliano Orri, Ophélie Collet, Judith van der Waerden, Maria Melchior, Michel Boivin, Richard E Tremblay, Sylvana M Côté

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Attention-deficit hyperactivity disorder and oral health in children and adolescents: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Large-scale evidence of a general disease ('Psychological medicine · 2025
    Article
  5. Article
  6. Article
  7. Annual Research Review: Perspectives on progress in ADHD science - from characterization to cause.Journal of child psychology and psychiatry, and allied disciplines · 2023
    Review
  8. Review
  9. Article
  10. Atopic dermatitis and risk of major neuropsychiatric disorders in children: A population-based cohort study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cédric Galéra *University of Bordeaux, Bordeaux, France. cedric.galera@u-bordeaux.fr.ORCID http://orcid.org/0000-0003-0549-9608
Samuele Cortese *University of Southampton, Solent NHS Trust, Southampton, UK.ORCID http://orcid.org/0000-0001-5877-8075
Massimiliano OrriINSERM, Bordeaux Population Health Center, UMR1219, Bordeaux, France.
Ophélie ColletSchool of Public Health, University of Montréal, Montréal, QC, Canada.
Judith van der WaerdenINSERM UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, Paris, France.
Maria MelchiorINSERM UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, Paris, France.
Michel BoivinResearch Unit on Children's Psychosocial Maladjustment, Montreal, QC, Canada.
Richard E TremblayResearch Unit on Children's Psychosocial Maladjustment, Montreal, QC, Canada.
Sylvana M CôtéINSERM, Bordeaux Population Health Center, UMR1219, Bordeaux, France.

Funding

CIHR
6 · The paper itself

Abstract

The comorbidity between physical and mental health conditions is challenging and frequently goes unrecognized in practice. Associations between Attention-Deficit/Hyperactivity Disorder (ADHD) and physical conditions have been reported in youth. However, prior research failed to: (1) address the patterns of associations in early childhood, middle childhood, and adolescence within the same population sample; (2) consider a large set of physical disorders at the same time; (3) take confounders into account. Our goal was to assess the associations between ADHD symptoms and a broad set of physical conditions across developmental periods. This birth cohort study (n = 2057) is the first to explore the associations between ADHD and a wide range of medical conditions by encompassing the whole early development from 5 months to 17 years in the same sample and relying on innovative network analyses. We found significant associations between ADHD symptoms and several physical conditions, some of which were observed in early childhood, middle childhood, and adolescence (e.g., asthma, sleep problems) or were confounded by socioeconomic status or psychiatric comorbidities (e.g., body mass index, dental caries). The study calls for an effective integrated care model encompassing mental and general healthcare across the developmental period.

Indexed as

Attention Deficit Disorder with HyperactivityDental CariesAdolescentChildChild, PreschoolCohort StudiesComorbidityHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.