ArticleScientific reports2021
Gut microbiota of bats: pro-mutagenic properties and possible frontiers in preventing emerging disease.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Detection of coronaviruses in insectivorous bats of Fore-Caucasus, 2021.Scientific reports · 2023Pooled it
- Bat-Inspired Longevity: Immune Damage Management and Nutritional Modulation for Healthy Aging.International journal of molecular sciences · 2026Review
- Seasonal Variation in the Mutagenic and Oxidative Properties of Gut Microbiota in Active and Hibernating Common Noctules (Nyctalus noctula).Current microbiology · 2026Article
- Virome and Microbiome of Florida Bats Illuminate Viral Co-Infections, Dietary Viral Signals, and Gut Microbiome Shifts.Microorganisms · 2025Article
- Bacterial Composition Across Bat Species: A Human Health Perspective.Animals : an open access journal from MDPI · 2025Review
- Article
- Metagenomic Investigation of Intestinal Microbiota of Insectivorous Synanthropic Bats: Densoviruses, Antibiotic Resistance Genes, and Functional Profiling of Gut Microbial Communities.International journal of molecular sciences · 2025Article
- Gut Microbiota Dynamics in Hibernating and ActiveVeterinary sciences · 2025Article
- Differences in gut microbiota composition, diversity, and predicted functional activity between wild and captive zoo Carollia perspicillata in a One Health perspective.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Ecological and public health dimensions of ESBL-producingVeterinary world · 2025Review
- Detection of Brno loanvirus (Loanvirus brunaense) in common noctule bats (Nyctalus noctula) in Southern Russia.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Soil microbiome characterization and its future directions with biosensing.Journal of biological engineering · 2024Article
- Comparative Analysis of the Gut Microbiota of Bat Species with Different Feeding Habits.Biology · 2024Article
- Gut Microbiota Composition of Insectivorous Synanthropic and Fructivorous Zoo Bats: A Direct Metagenomic Comparison.International journal of molecular sciences · 2023Article
- Review
- Cultivable Gut Microbiota in Synanthropic Bats: Shifts of Its Composition and Diversity Associated with Hibernation.Animals : an open access journal from MDPI · 2023Article
- The COVID misinfodemic: not new, never more lethal.Trends in microbiology · 2022Review
- Coronavirus Infections in Animals: Risks of Direct and Reverse Zoonoses.Herald of the Russian Academy of Sciences · 2022Article
- An overview of bats microbiota and its implication in transmissible diseases.Frontiers in microbiology · 2022Review
- Beneficial Effects of Spore-FormingFrontiers in veterinary science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
Bats are potential natural reservoirs for emerging viruses, causing deadly human diseases, such as COVID-19, MERS, SARS, Nipah, Hendra, and Ebola infections. The fundamental mechanisms by which bats are considered "living bioreactors" for emerging viruses are not fully understood. Some studies suggest that tolerance to viruses is linked to suppressing antiviral immune and inflammatory responses due to DNA damage by energy generated to fly. Our study reveals that bats' gut bacteria could also be involved in the host and its microbiota's DNA damage. We performed screening of lactic acid bacteria and bacilli isolated from bats' feces for mutagenic and oxidative activity by lux-biosensors. The pro-mutagenic activity was determined when expression of recA increased with the appearance of double-strand breaks in the cell DNA, while an increase of katG expression in the presence of hydroxyl radicals indicated antioxidant activity. We identified that most of the isolated bacteria have pro-mutagenic and antioxidant properties at the same time. This study reveals new insights into bat gut microbiota's potential involvement in antiviral response and opens new frontiers in preventing emerging diseases originating from bats.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.