ArticleScientific reports2021
Effect of the over-dominant expression of proteins on nicotine heterosis via proteomic analysis.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Overexpression of NtGSTU10 gene enhances nicotine content in hybrids by promoting the synthesis and transport metabolism of nicotine.BMC biotechnology · 2025Article
- The formation of nicotine heterosis is mainly achieved by enhancing the nicotine transport capacity in hybrids.BMC plant biology · 2024Article
- Non-additive expression genes play a critical role in leaf vein ratio heterosis in Nicotiana tabacum L.BMC genomics · 2024Article
- Article
- Overdominant expression of genes plays a key role in root growth of tobacco hybrids.Frontiers in plant science · 2023Article
- Overdominant expression of related genes of ion homeostasis improves KBMC plant biology · 2022Article
- Proteomics and Co-expression Network Analysis Reveal the Importance of Hub Proteins and Metabolic Pathways in Nicotine Synthesis and Accumulation in Tobacco (Frontiers in plant science · 2022Article
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8 authors at 2 institutions in 1 country.
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Abstract
Heterosis is a common biological phenomenon that can be used to optimize yield and quality of crops. Using heterosis breeding, hybrids with suitable nicotine content have been applied to tobacco leaf production. However, the molecular mechanism of the formation of nicotine heterosis has never been explained from the perspective of protein. The DIA proteomics technique was used to compare the differential proteomics of the hybrid Va116 × Basma, showing strong heterosis in nicotine content from its parent lines Va116 and Basma. Proteomics analysis indicated that 65.2% of DEPs showed over-dominant expression patterns, and these DEPs included QS, BBL, GS, ARAF and RFC1 which related to nicotine synthesis. In addition, some DEPs (including GST, ABCE2 and ABCF1 and SLY1) that may be associated with nicotinic transport exhibited significant heterosis over the parental lines. These findings demonstrated that the efficiency of the synthesis and transport of nicotine in hybrids was significantly higher than that in the parent lines, and the accumulation of over-dominant expression proteins may be the cause of heterosis of nicotinic content in hybrids.
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