Evidence map›Paper›PMID 34702754›Full record

ArticleBMJ (Clinical research ed.)2021

Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration.

Veronika W Skrivankova, Rebecca C Richmond, Benjamin A R Woolf, Neil M Davies, Sonja A Swanson, Tyler J VanderWeele, Nicholas J Timpson, Julian P T Higgins, Niki Dimou, Claudia Langenberg and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ (Clinical research ed.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,021 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,021citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,021 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
  2. Assessing the causal effects of environmental tobacco smoke exposure: a meta-analytic Mendelian randomization study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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961 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Veronika W SkrivankovaInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Rebecca C RichmondMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Benjamin A R WoolfMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Neil M DaviesMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Sonja A SwansonDepartment of Epidemiology, Erasmus MC, Rotterdam, Netherlands.
Tyler J VanderWeeleDepartment of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA.
Nicholas J TimpsonMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Julian P T HigginsPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Niki DimouNutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France.
Claudia LangenbergBerlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.
Elizabeth W LoderHarvard Medical School, Boston, MA, USA.
Robert M GolubJAMA, Chicago, IL, USA.
Matthias EggerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
George Davey SmithMedical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
J Brent RichardsDepartments of Medicine, Human Genetics, Epidemiology & Biostatistics, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, QC, Canada contact@strobe-mr.org.ORCID 0000-0002-3746-9086

Funding

Theory and methods for mediation and interactionR01CA222147 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI TCHETGEN TCHETGEN, ERIC JOEL, VANDERWEELE, TYLER · 2018 to 2022
$2.1M
Cancer Research UK 19169Cancer Research UK 29019Medical Research Council MC_UU_00006/1Medical Research Council MC_UU_00011/1Medical Research Council MC_UU_00011/2Medical Research Council MC_UU_00011/5Medical Research Council MC_UU_00011/6Medical Research Council MC_UU_00011/7Medical Research Council MR/M005070/1NCI NIH HHS R01 CA222147World Health Organization 001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epidemiologic Research DesignGuidelines as TopicHumansMendelian Randomization AnalysisObservational Studies as Topic

Identifiers

PMID34702754
PMCPMC8546498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.