ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Subthalamic-Cortical Network Reorganization during Parkinson's Tremor.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed.
- Intelligent differentiation between Parkinson's disease and essential tremor using wearable sensors and machine learning: a temporal validation study.BMC medical informatics and decision making · 2026Article
- Tremor pathophysiology.Clinical parkinsonism & related disorders · 2026Review
- Local field potential biomarkers for adaptive deep brain stimulation in Parkinson's disease: A scoping review.Surgical neurology international · 2026Review
- Phenotypical Differentiation of Tremor Using Time Series Feature Extraction and Machine Learning.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Reliability of Neuroimaging and Neurophysiological Tremor Features in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Changes in Action Tremor in Parkinson's Disease over Time: Clinical and Neuroimaging Correlates.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Dysfunction of motor cortices in Parkinson's disease.Cerebral cortex (New York, N.Y. : 1991) · 2024Review
- Article
- Reconstructing Re-emergent Tremor.Movement disorders clinical practice · 2023Article
- Integrative Brain States Facilitate the Expression of Parkinson's Tremor.Movement disorders : official journal of the Movement Disorder Society · 2023Article
- Article
- T-type calcium channels as therapeutic targets in essential tremor and Parkinson's disease.Annals of clinical and translational neurology · 2023Review
- Clinical neurophysiology of Parkinson's disease and parkinsonism.Clinical neurophysiology practice · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Tremor, a common and often primary symptom of Parkinson's disease, has been modeled with distinct onset and maintenance dynamics. To identify the neurophysiologic correlates of each state, we acquired intraoperative cortical and subthalamic nucleus recordings from 10 patients (9 male, 1 female) performing a naturalistic visual-motor task. From this task, we isolated short epochs of tremor onset and sustained tremor. Comparing these epochs, we found that the subthalamic nucleus was central to tremor onset, as it drove both motor cortical activity and tremor output. Once tremor became sustained, control of tremor shifted to cortex. At the same time, changes in directed functional connectivity across sensorimotor cortex further distinguished the sustained tremor state.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.