Evidence map›Paper›PMID 34702735›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Tumorigenesis and cell competition in

Izarne Medina, Manuel Calleja, Ginés Morata

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Epigenetic Regulation in Drosophila Tumor Models.Advances in experimental medicine and biology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Profile of Ginés Morata.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Izarne MedinaCentro de Biología Molecular, Consejo Superior de Investigaciones Científicas-Universidad Autónoma Madrid, 28049 Madrid, Spain.
Manuel CallejaCentro de Biología Molecular, Consejo Superior de Investigaciones Científicas-Universidad Autónoma Madrid, 28049 Madrid, Spain.
Ginés MorataCentro de Biología Molecular, Consejo Superior de Investigaciones Científicas-Universidad Autónoma Madrid, 28049 Madrid, Spain gmorata@cbm.csic.es.
Centro de Biología Molecular Severo Ochoa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell competition is a homeostatic process that eliminates by apoptosis unfit or undesirable cells from animal tissues, including tumor cells that appear during the life of the organism. In

Indexed as

CarcinogenesisCell CompetitionAnimalsApoptosisDNA-Binding ProteinsDrosophilaDrosophila ProteinsImaginal DiscsMAP Kinase Signaling SystemPolycomb Repressive Complex 1DNA-Binding ProteinsDrosophila Proteinsph-d protein, Drosophilaph-p protein, DrosophilaPolycomb Repressive Complex 1cell competitionJNKpolyhomeotictumors

Identifiers

PMID34702735
PMCPMC8609302
OpenAlexW3210554603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.