ArticleBMC pharmacology & toxicology2021
Identification and solution of drug-related problems in the neurology unit of a tertiary hospital in China.
Article in BMC pharmacology & toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Trial
- Development and validation of a machine learning-based clinical decision support tool for stratifying intravenous medication risk in hospitalized patients with heart failure.International journal of clinical pharmacy · 2026Article
- Drug-related problems in pediatric patients with chronic kidney disease: A single-center prospective study.Experimental and therapeutic medicine · 2026Article
- Article
- Development and evaluation of the pharmacist intervention evaluation (PIE) system: a modified classification for drug-related problems in Chinese tertiary hospitals.Frontiers in pharmacology · 2026Article
- Identification of Drug-Related Problems and Assessment of Health-Related Quality of Life in Elderly Multimorbid Inpatients with Stroke.Integrated pharmacy research & practice · 2026Article
- Study on risk factors and associated drug related problems in patients with stroke.BMC neurology · 2025Article
- Risk factors for gastrointestinal complications during glucocorticoid therapy in internal medicine inpatients: a real-world retrospective analysis.BMC pharmacology & toxicology · 2025Article
- Identification and resolution of drug-related problems in the cardiovascular surgery unit of a tertiary hospital in China: a retrospective study.Journal of cardiothoracic surgery · 2025Article
- Impact of clinical pharmacist interventions on medication administration via enteral feeding tubes in a neurology ward: a pre- and post-educational prospective study.Frontiers in pharmacology · 2025Article
- Assessment of drug-related problems among breast cancer patients in a cancer specialty center in Nepal.PloS one · 2025Article
- Drug-Related Problems in HIV Treatment Failure.Cureus · 2024Article
- Analysis of inappropriate prophylactic use of proton pump inhibitors during the perioperative period: an observational study.Perioperative medicine (London, England) · 2024Article
- Drug-related problems identified by clinical pharmacists in an academic medical centre in Thailand.Journal of pharmaceutical policy and practice · 2024Article
- Drug-related problems among type 2 diabetic patients in Sunwal Municipality of Western Nepal.PloS one · 2024Article
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Authors and funding
4 authors.
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Abstract
backgroundThe prevalence and characteristics of drug-related problems (DRPs) and factors associated with the occurrence of DRPs in the neurology unit in China remain unknown. This study aimed to determine the prevalence, characteristics and severity ratings of DRPs and identify factors associated with the occurrence of DRPs in the neurology unit of a tertiary care and academic teaching hospital in China.
methodsA retrospective study of DRPs and pharmacists' interventions for neurology patients was performed during a non-consecutive 24-month study period. Patient demographics and clinical characteristics, and pharmacist's intervention records were collected. The characteristics and severity ratings of DRPs were categorized using the Pharmaceutical Care Network Europe (PCNE) DRP classification tool V9.00 and the National Coordinating Council for Medication Error Reporting and Prevention (NCC-MERP) classification respectively.
resultsA total of 242 DRPs were detected for 974 admitted patients, an average of 0.25 DRPs per patient. Treatment safety was the major type of DRPs (106;43.8%) followed by treatment effectiveness (78;32.2%). The primary causes of DRPs were drug selection (124;44.1%) and dose selection (92;32.7%). Clinical pharmacists provided 525 interventions, and most interventions occurred at the prescriber level (241;45.9%). A total of 91.4% of these interventions were accepted, contributing to solving 93.0% of the identified problems. The majority of DRPs (210;86.8%) were rated at severity categories B to D (causing no patient harm). Multiple logistic regression showed that creatinine clearance, number of medications used, nasogastric feeding, diabetes, and infectious diseases were associated with more frequent DRPs (p < 0.05).
conclusionsDRPs are relatively common in the neurology unit in China, with primary causes of drug and dose selection, and clinical pharmacists can effectively reduce and prevent DRPs to optimize medication therapy.
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