Evidence map›Paper›PMID 34702347›Full record

ArticleSystematic reviews2021

HIV incidence among men who have sex with men in mainland China: a systematic review protocol.

Wenting Huang, Liming Wang, Mi Guodong, Ryan J Zahn, Jennifer Taussig, Shenita R Peterson, Stefan Baral, Renee H Moore, Xiaojie Huang, Jianhua Hou and 2 more

Abstract read
In one paragraph

Article in Systematic reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenting HuangDepartment of Behavioral Sciences and Health Education, Emory University, Atlanta, GA, 1518 Clifton Road, Atlanta, GA, 30322, USA.
Liming WangBeijing Danlan Media Limited, Beijing, China.
Mi GuodongBeijing Danlan Media Limited, Beijing, China.
Ryan J ZahnDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA.
Jennifer TaussigDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA.
Shenita R PetersonWoodruff Health Sciences Center Library, Emory University, Atlanta, USA.
Stefan BaralDepartment of Epidemiology, John Hopkins School of Public Health, Baltimore, USA.
Renee H MooreBiostatistics and Bioinformatics, Emory University, Atlanta, USA.
Xiaojie HuangBeijing YouAn Hospital, Capital Medical University, Beijing, China.
Jianhua HouBeijing YouAn Hospital, Capital Medical University, Beijing, China.
Patrick S SullivanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA.
Aaron J SieglerDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA. asiegle@emory.edu.ORCID 0000-0001-5553-7540

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
Population-based survey of SARS-CoV-2 infection and immune responseR01AI143875 · NIAID · EMORY UNIVERSITY · PI SIEGLER, AARON JULIUS, SULLIVAN, PATRICK SEAN · 2019 to 2023
$9.2M
NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI143875
6 · The paper itself

Abstract

backgroundMen who have sex with men (MSM) are disproportionately affected by HIV in China. Globally, younger MSM are at higher risk for incident HIV infections, but there has been substantial variation in the estimates of age-stratified HIV incidence among MSM in mainland China, potentially due to regional differences in the nature of the epidemic. Given the need for quality epidemiological data to meet the global goal of ending new HIV infections by 2030, this systematic review and meta-analysis aims to determine age-stratified HIV incidence in mainland China, including consideration by geographic region and time.

methodsThis review will include longitudinal studies, cross-sectional surveys, and surveillance reports among MSM in mainland China that have reported HIV incidence. We will search studies and reports published from January 1, 2003, to April 30, 2020, in both English and Chinese language literature databases. For each study considered, two reviewers will independently screen, determine eligibility, and extract relevant data, with discrepancies resolved by consensus of a third reviewer. The methodological quality of included studies will be assessed by the Quality Assessment Tool for Systematic Reviews of Observational Studies Score (QATSO). We will develop age-stratified estimates of HIV incidence with geographic variations and temporal trends. Heterogeneity will be examined using statistical techniques appropriate to the dataset. For subgroup analyses, we will conduct mixed-effects meta-analysis models. DISCUSSION: This review will contribute to a better understanding of the HIV epidemic among MSM in mainland China by providing age-stratified estimates of HIV incidence with a portrayal of geographic and temporal variations. Findings will reflect epidemic dynamics, informing local and national intervention programs and policies for HIV prevention, and providing estimation data to inform future research among MSM in China. SYSTEMATIC REVIEW REGISTRATION: PROSPERO ID 154834.

Indexed as

HIV InfectionsSexual and Gender MinoritiesCross-Sectional StudiesHomosexuality, MaleHumansIncidenceMaleMeta-Analysis as TopicReview Literature as TopicSystematic Reviews as TopicChinaEpidemiologyHIVIncidenceMSM

Identifiers

PMID34702347
PMCPMC8549324

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.