Evidence map›Paper›PMID 34702307›Full record

ArticleAnnals of clinical microbiology and antimicrobials2021

Prevalence of β-lactamase-encoding genes and molecular typing of Acinetobacter baumannii isolates carrying carbapenemase OXA-24 in children.

Neda Yousefi Nojookambari, Mehrzad Sadredinamin, Razieh Dehbanipour, Zohreh Ghalavand, Gita Eslami, Maryam Vaezjalali, Bahram Nikmanesh, Sajjad Yazdansetad

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Comparative analysis ofFrontiers in microbiology · 2025
    Article
  8. Article
  9. Article
  10. Analysis of carbapenem-resistantInternational journal of molecular epidemiology and genetics · 2024
    Article
  11. Does Emerging Carbapenem Resistance inInfectious disease reports · 2023
    Review
  12. Genotypic Patterns of Multidrug-ResistantAdvanced biomedical research · 2023
    Review
  13. Article
  14. Outbreak of Multidrug-resistantAnnals of African medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Neda Yousefi NojookambariDepartment of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-6321-598X
Mehrzad SadredinaminDepartment of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-6393-6733
Razieh DehbanipourDepartment of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-8678-0399
Zohreh GhalavandDepartment of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. zghalavand@sbmu.ac.ir.ORCID http://orcid.org/0000-0002-1998-2716
Gita EslamiDepartment of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-5013-5267
Maryam VaezjalaliDepartment of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0003-3370-7566
Bahram NikmaneshDepartment of Medical Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-7035-6633
Sajjad YazdansetadLaboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.ORCID http://orcid.org/0000-0002-1087-3054
Shahid Beheshti University of Medical Sciences · IRGolestan University · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundβ-Lactam antibiotics have been broadly used for the treatment of Acinetobacter baumannii infections, resulting in development of β-lactam inactivating β-lactamases. Here, we described antibiotic resistance rate, prevalence of β-lactamase-encoding genes, and clonal relationships of A. baumannii strains isolated from children referred to Children's Medical Center in Tehran, Iran, during 2019-2020.

methodsA total of 60 non-replicate A. baumannii isolates were recovered from clinical specimens of pediatric patients. Antibiotic susceptibility testing was done by the disc diffusion method. Colistin susceptibility of isolates was performed by the broth microdilution method. β-lactamase-encoding genes were characterized by PCR. The presence of ISAba1 element upstream of the several oxacillinase genes was also checked. Genetic relatedness of isolates was determined by using random amplification of polymorphic DNA (RAPD) typing.

resultsThe antimicrobial susceptibility tests showed that 83.3% of A. baumannii isolates were MDR, and 40% XDR. Both MDR and XDR A. baumannii isolates were susceptible to colistin. The frequency of bla

conclusionsThe multiple clones harboring bla

Indexed as

Acinetobacter baumanniiBacterial Proteinsbeta-Lactamasesbeta-LactamsChildColistinHumansIranMolecular TypingPrevalenceRandom Amplified Polymorphic DNA TechniqueBacterial Proteinsbeta-Lactamasesbeta-LactamscarbapenemaseColistinAcinetobacter baumanniiAntimicrobial susceptibilitybla OXA-24-likePediatricsRAPD-PCRβ-Lactamases

Identifiers

PMID34702307
PMCPMC8549256
OpenAlexW3210429138

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.