Evidence map›Paper›PMID 34702284›Full record

ArticleAIDS research and therapy2021

Acute HIV infection syndrome mimicking COVID-19 vaccination side effects: a case report.

Julian Triebelhorn, Stefanie Haschka, Felix Hesse, Johanna Erber, Simon Weidlich, Marcel Lee, Dieter Hoffmann, Josef Eberle, Christoph D Spinner

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS research and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Julian TriebelhornDepartment of Internal Medicine II, University Hospital Rechts Der Isar, School of Medicine, Technical University of Munich, Ismaninger-Straße 22, 93675, Munich, Germany. julian.triebelhorn@mri.tum.de.
Stefanie HaschkaDepartment of Internal Medicine II, University Hospital Rechts Der Isar, School of Medicine, Technical University of Munich, Ismaninger-Straße 22, 93675, Munich, Germany.
Felix HesseDepartment of Internal Medicine II, University Hospital Rechts Der Isar, School of Medicine, Technical University of Munich, Ismaninger-Straße 22, 93675, Munich, Germany.
Johanna ErberDepartment of Internal Medicine II, University Hospital Rechts Der Isar, School of Medicine, Technical University of Munich, Ismaninger-Straße 22, 93675, Munich, Germany.
Simon WeidlichDepartment of Internal Medicine II, University Hospital Rechts Der Isar, School of Medicine, Technical University of Munich, Ismaninger-Straße 22, 93675, Munich, Germany.
Marcel LeeDepartment of Internal Medicine II, University Hospital Rechts Der Isar, School of Medicine, Technical University of Munich, Ismaninger-Straße 22, 93675, Munich, Germany.
Dieter HoffmannInstitute of Virology, School of Medicine, Technical University of Munich, Munich, Germany.
Josef EberleMax Von Pettenkofer Institute, German National Reference Centre for Retroviruses at Ludwig Maximilian University of München, Munich, Germany.
Christoph D SpinnerDepartment of Internal Medicine II, University Hospital Rechts Der Isar, School of Medicine, Technical University of Munich, Ismaninger-Straße 22, 93675, Munich, Germany.
Technical University of Munich · DEKlinikum rechts der Isar · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSymptoms of primary HIV infection, including fever, rash, and headache, are nonspecific and are often described as flu-like. COVID-19 vaccination side effects, such as fever, which occur in up to 10% of people following COVID-19 vaccination, can make the diagnosis of acute HIV infection even more challenging. CASE PRESENTATION: A 26-year-old man presented with fever and headache following COVID-19 vaccination. The symptoms were initially thought to be vaccine side effects. A diagnostic workup was conducted due to persisting fever and headache > 72 h following vaccination, and he was diagnosed with Fiebig stage II acute HIV infection, 3 weeks after having unprotected anal intercourse with another man.

conclusionThorough anamnesis is key to estimating the individual risk of primary HIV infection, in patients presenting with flu-like symptoms. Early diagnosis and initiation of antiretroviral therapy is associated with better prognosis and limits transmission of the disease.

Indexed as

COVID-19HIV InfectionsAdultCOVID-19 VaccinesHumansMaleSARS-CoV-2VaccinationCOVID-19 VaccinesAcute HIV infectionCOVID-19FiebigHIV seroconversion illnessSeroconversionVaccination

Identifiers

PMID34702284
PMCPMC8547722
OpenAlexW3197182195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.