Evidence map›Paper›PMID 34702236›Full record

ArticleBMC pulmonary medicine2021

Determination of oxygen saturation compared to a prescribed target range using continuous pulse oximetry in acutely unwell medical patients.

James C P Harper, Ruth Semprini, Nethmi A Kearns, Lee Hatter, Grace E Bird, Irene Braithwaite, Allie Eathorne, Mark Weatherall, Richard Beasley

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Manual compared to automated closed-loop oxygen control strategies in hospitalised adults: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Trial
  3. Article
  4. Effect of automated titration of oxygen on time spent in a prescribed oxygen saturation range in adults in the ICU after cardiac surgery.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

James C P HarperMedical Research Institute of New Zealand, Private Bag 7902, Newtown, Wellington, 6242, New Zealand. James.Harper@mrinz.ac.nz.
Ruth SempriniMedical Research Institute of New Zealand, Private Bag 7902, Newtown, Wellington, 6242, New Zealand.
Nethmi A KearnsMedical Research Institute of New Zealand, Private Bag 7902, Newtown, Wellington, 6242, New Zealand.
Lee HatterMedical Research Institute of New Zealand, Private Bag 7902, Newtown, Wellington, 6242, New Zealand.
Grace E BirdMedical Research Institute of New Zealand, Private Bag 7902, Newtown, Wellington, 6242, New Zealand.
Irene BraithwaiteMedical Research Institute of New Zealand, Private Bag 7902, Newtown, Wellington, 6242, New Zealand.
Allie EathorneMedical Research Institute of New Zealand, Private Bag 7902, Newtown, Wellington, 6242, New Zealand.
Mark WeatherallUniversity of Otago Wellington, Wellington, New Zealand.
Richard BeasleyMedical Research Institute of New Zealand, Private Bag 7902, Newtown, Wellington, 6242, New Zealand.
Medical Research Institute of New Zealand · NZHutt Hospital · NZUniversity of Otago · NZ

Funding

Health Research Council of New Zealand 18/002
6 · The paper itself

Abstract

backgroundBoth inadequate and excessive administration of oxygen to acutely unwell patients results in risk of harm. Guidelines recommend titration of oxygen to achieve a target oxygen saturation (SpO

methodsIn this two-centre non-interventional study we used continuous pulse oximetry in acutely unwell medical patients over a 24-h period to determine the proportion of time spent with SpO

resultsEighty participants were included in the analysis. The mean (SD) proportion of time spent in target range was 55.6% (23.6), this was lower in those with a reduced hypercapnic target range (88-92% or below) compared to those with a range of 92-96%; difference - 13.1% (95% CI - 3.0 to - 23.2), P = 0.012. The proportion of time spent above range was 16.2% (22.9); this was higher in those with a reduced hypercapnic range; difference 21.6% (31.4 to 12), P < 0.001. The proportion of time below range was 28.4% (25.2); there was no difference between target ranges. The proportion of time spent in range was higher for those in a high dependency area in the multivariate model; difference 15.5% (95% CI 2.3 to 28.7), P = 0.02.

conclusionsMedical patients receiving oxygen in a ward setting spend significant periods of time with SpO

Indexed as

Acute DiseaseAgedAged, 80 and overFemaleHumansHypercapniaMaleNew ZealandOximetryOxygenOxygen Inhalation TherapyOxygen SaturationPulmonary Disease, Chronic ObstructiveTimeOxygenOxygen saturationTarget range

Identifiers

PMID34702236
PMCPMC8546386
OpenAlexW3209910271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.