Evidence map›Paper›PMID 34702203›Full record

ArticleBMC pregnancy and childbirth2021

Trimester-specific reference ranges for thyroid hormones of pregnant females at tertiary care hospitals in Lahore, Pakistan.

Asim Mumtaz, Fauzia Sadiq, Saima Zaki, Hijab Batool, Muhammad Ibrahim, Muhammad Khurram, Usman Ayub Awan, Kiran Saeed, Muhammad Sohail Afzal

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Asim MumtazDepartment of Pathology Akhtar Saeed Medical College, Lahore, Pakistan.
Fauzia SadiqLahore Medical & Dental College, Lahore, Pakistan.
Saima ZakiDepartment of Gynae & OBS Jinnah Hospital Lahore, Lahore, Pakistan.
Hijab BatoolCentral Park Medical College, Lahore, Pakistan.
Muhammad IbrahimDepartment of Biostatistics, School of Alibied Health Sciences, Children Hospital Lahore, Lahore, Pakistan.
Muhammad KhurramDepartment of Life Sciences, School of Science, University of Management and Technology (UMT), Lahore, Postal Code # 54700, Pakistan.
Usman Ayub AwanDepartment of Medical Laboratory Technology, The University of Haripur, Haripur, Khyber Pakhtunkhwa, Pakistan.
Kiran SaeedUniversity of Lahore, Lahore, Pakistan.
Muhammad Sohail AfzalDepartment of Life Sciences, School of Science, University of Management and Technology (UMT), Lahore, Postal Code # 54700, Pakistan. sohail.ncvi@gmail.com.ORCID https://orcid.org/0000-0001-9807-5710
CMH Lahore Medical College and Institute of Dentistry · PKFarooq Hospital · PKJinnah Postgraduate Medical Center · PKMayo Hospital · PKUniversity of Haripur · PKUniversity of Lahore · PKUniversity of Management and Technology · PKUniversity of Management and Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe significance of investigation for diagnosing and managing thyroid dysfunction in pregnant females has been extensively documented in the medical literature. This study aimed to determine trimester-specific reference ranges for thyroid-stimulating hormones (TSH), free T

methodsThis cross-sectional study was conducted at two tertiary care Hospitals in Lahore, Pakistan. In this multi-centric study, 500 pregnant females were initially enrolled from September 2019 to December 2019 who fulfilled the inclusion criteria. For measurement of serum FT

resultsOut of 500 subjects, 23 subjects with positive anti-TPO, 19 subjects with anti-TG antibodies, and 12 subjects due to less volume of serum yielded from whole blood (serum less than 3 ml) were excluded from the analysis. Ten samples were hemolyzed and not included in the analysis. A total of 436 samples were examined for analysis. Of the remaining 436 subjects, 133 (30.5%) were from 1st trimester, 153 (35.1%) from 2nd trimester, and 150 (34.4%) from 3rd trimester. As the data were non-normal, the 2.5th, 50th, and 97.5th percentiles were calculated to express each group's results. Trimester specific range of TSH 0.168-4.294, 0.258-4.584 and 0.341-4.625 mIU/mL, FT

conclusionIn this study, we established a trimester-specific reference range for our local population's thyroid function test. The results of this study have complemented the results of previous studies.

Indexed as

AdultCross-Sectional StudiesFemaleHumansPakistanPregnancyPregnancy TrimestersReference ValuesTertiary Care CentersThyroid Function TestsThyroid HormonesThyrotropinThyroxineTriiodothyronineThyroid HormonesThyrotropinThyroxineTriiodothyronineFT3FT4PakistanPregnancyReference RangeThyroid function testTSH

Identifiers

PMID34702203
PMCPMC8547102
OpenAlexW3209920871

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.