Evidence map›Paper›PMID 34700373›Full record

ArticlemBio2021

Identification of ZDHHC17 as a Potential Drug Target for Swine Acute Diarrhea Syndrome Coronavirus Infection.

Yun Luo, Chee Wah Tan, Shi-Zhe Xie, Ying Chen, Yu-Lin Yao, Kai Zhao, Yan Zhu, Qi Wang, Mei-Qin Liu, Xing-Lou Yang and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Research Advances on Swine Acute Diarrhea Syndrome Coronavirus.Animals : an open access journal from MDPI · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Genomewide CRISPR knockout screen identified PLAC8 as an essential factor for SADS-CoVs infection.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Yun Luo *CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0002-6243-7000
Chee Wah Tan *Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.
Shi-Zhe Xie *CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Ying ChenCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Yu-Lin YaoCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Kai ZhaoCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Yan ZhuCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Qi WangCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Mei-Qin LiuCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Xing-Lou YangCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Lin-Fa WangProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID 0000-0003-2752-0535
Zheng-Li ShiCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0001-8089-163X
Chinese Academy of Sciences · CNDuke-NUS Medical School · SG

Funding

National Natural Science Foundation of China (NSFC) 31830096National Research Foundation Singapore (NRF) NRF2012NRF-CRP001-056National Research Foundation Singapore (NRF) NRF2016NRF-NSFC002-013
6 · The paper itself

Abstract

The recent emergence and spread of zoonotic viruses highlights that animal-sourced viruses are the biggest threat to global public health. Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an HKU2-related bat coronavirus that was spilled over from

Indexed as

AcyltransferasesAdaptor Proteins, Signal TransducingAlphacoronavirusAnimalsCOVID-19HeLa CellsHumansMiddle East Respiratory Syndrome CoronavirusNerve Tissue ProteinsPalmitatesSARS-CoV-2Severe acute respiratory syndrome-related coronavirusSwine2-bromopalmitateAcyltransferasesAdaptor Proteins, Signal TransducingNerve Tissue ProteinsPalmitatesZDHHC17 protein, human2-bromopalmitateCRISPR-Cas9 screenDHHC domainSADS-CoV

Identifiers

PMID34700373
PMCPMC8546599
OpenAlexW3208061035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.