Evidence map›Paper›PMID 34700360›Full record

ArticleAnaesthesia2022

Quantitative evaluation of aerosol generation during manual facemask ventilation.

A J Shrimpton, J M Brown, F K A Gregson, T M Cook, D A Scott, F McGain, R S Humphries, R S Dhillon, J P Reid, F Hamilton and 3 more

Abstract read
In one paragraph

Article in Anaesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

A J ShrimptonAnaesthesia, Pain and Critical Care Sciences, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.ORCID 0000-0001-6790-909X
J M BrownDepartment of Anaesthesia and Intensive Care Medicine, North Bristol NHS Trust, Bristol, UK.
F K A GregsonSchool of Chemistry, University of Bristol, Bristol, UK.ORCID 0000-0002-8516-0796
T M CookDepartment of Anaesthesia and Intensive Care Medicine, Royal United Hospital NHS Trust, Bath, UK.ORCID 0000-0002-3654-497X
D A ScottDepartment of Critical Care, University of Melbourne; St. Vincent's Hospital Melbourne, Australia.ORCID 0000-0001-6637-0029
F McGainWestern Health, Footscray, Victoria, Australia.ORCID 0000-0002-1977-9072
R S HumphriesClimate Science Centre, CSIRO Oceans and Atmosphere, Aspendale, Victoria, Australia.
R S DhillonDepartment of Neurosurgery, St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia.ORCID 0000-0002-6975-8325
J P ReidSchool of Chemistry, University of Bristol, Bristol, UK.ORCID 0000-0001-6022-1778
F HamiltonDepartment of Population Health Sciences, University of Bristol, Bristol, UK.ORCID 0000-0002-9760-4059
B R BzdekSchool of Chemistry, University of Bristol, Bristol, UK.ORCID 0000-0003-2234-1079
A E PickeringAnaesthesia, Pain and Critical Care Sciences, School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.ORCID 0000-0003-0345-0456
AERATOR study group

Funding

Medical Research Council MR/T005114/1
6 · The paper itself

Abstract

Manual facemask ventilation, a core component of elective and emergency airway management, is classified as an aerosol-generating procedure. This designation is based on one epidemiological study suggesting an association between facemask ventilation and transmission during the SARS-CoV-1 outbreak in 2003. There is no direct evidence to indicate whether facemask ventilation is a high-risk procedure for aerosol generation. We conducted aerosol monitoring during routine facemask ventilation and facemask ventilation with an intentionally generated leak in anaesthetised patients. Recordings were made in ultraclean operating theatres and compared against the aerosol generated by tidal breathing and cough manoeuvres. Respiratory aerosol from tidal breathing in 11 patients was reliably detected above the very low background particle concentrations with median [IQR (range)] particle counts of 191 (77-486 [4-1313]) and 2 (1-5 [0-13]) particles.l

Indexed as

MasksAdultAgedCoughFemaleHumansMaleMiddle AgedRespiratory Aerosols and DropletsSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirusaerosol-generating procedureCOVID-19facemask ventilationmanual ventilationSARS-CoV-2

Identifiers

PMID34700360
PMCPMC8653000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.