Evidence map›Paper›PMID 34700347›Full record

ArticleAmerican journal on intellectual and developmental disabilities2021

Motor Influences on Communication: Comparisons Between Down Syndrome and Fragile X Syndrome.

Elizabeth A Will, Jane E Roberts

Open access · greenAbstract read
In one paragraph

Article in American journal on intellectual and developmental disabilities, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Prelinguistic Communication Complexity of Children With Neurogenetic Syndromes.Journal of speech, language, and hearing research : JSLHR · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elizabeth A WillElizabeth A. Will and Jane E. Roberts, University of South Carolina.
Jane E RobertsElizabeth A. Will and Jane E. Roberts, University of South Carolina.
Elizabeth City State University · US

Funding

Emergence, Stability and Predictors of Anxiety in Fragile X SyndromeR01MH107573 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI Abigail Lee Hogan · 2016 to 2026
$6.1M
Supplement to The Emergence and Stability of Autism in Fragile X SyndromeR01MH090194 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ROBERTS, JANE E · 2011 to 2020
$5.4M
Early Features of Autism Risk in Down SyndromeF32HD097877 · NICHD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI WILL, ELIZABETH · 2018 to 2021
$175k
NICHD NIH HHS F32 HD097877NICHD NIH HHS L40 HD103202NIMH NIH HHS L40 MH117727NIMH NIH HHS R01 MH090194NIMH NIH HHS R01 MH107573
6 · The paper itself

Abstract

Motor skills, an important foundation for language and communication, are considerably delayed in children with Down syndrome (DS) and fragile X syndrome (FXS). However, the impact of these impairments on expressive and receptive communication and the phenotypic specificity of these associations remains unknown. Participants included 37 with DS and 37 age and developmentally matched children with FXS. Syndrome-specific motor and communication profiles emerged, with higher communication scores seen in the DS versus FXS on, but lower gross motor scores. Significant associations between domains of motor and communication were identified for both groups with additional phenotype-specific patterns. Findings demonstrate the importance of early motor abilities for communication in DS and FXS. Implications for phenotypic specificity and targeted intervention are discussed.

Indexed as

Down SyndromeFragile X SyndromeCommunicationHumansLanguageLanguage DevelopmentcommunicationDown syndromefragile X syndromemotorphenotypic specificity

Identifiers

PMID34700347
PMCPMC8764748
OpenAlexW3209130587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.