Evidence map›Paper›PMID 34699851›Full record

ArticleJournal of affective disorders2022

Personalized networks of social anxiety disorder and depression and implications for treatment.

Marilyn L Piccirillo, Thomas L Rodebaugh

Abstract read
In one paragraph

Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Relations among daily symptoms of depression.British journal of psychology (London, England : 1953) · 2026
    Article
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  14. Using the experience sampling method to support clinical practice: An illustration with problematic cannabis use.Psychotherapy research : journal of the Society for Psychotherapy Research · 2024
    Article
  15. Article
  16. Investigating Individual Variation Using Dynamic Structural Equation Modeling: A Tutorial with Tinnitus.Clinical psychological science : a journal of the Association for Psychological Science · 2023
    Article
  17. Regulatory Molecules of Synaptic Plasticity in Anxiety Disorder.International journal of general medicine · 2023
    Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marilyn L PiccirilloDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA. Electronic address: piccirim@uw.edu.
Thomas L RodebaughDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA.

Funding

Psychology Training in Alcohol Research (PTAR)T32AA007455 · NIAAA · UNIVERSITY OF WASHINGTON · PI MARY E. LARIMER · 1985 to 2026
$11.4M
Digital Phenotyping of Anxiety and Anxiety-Related Alcohol Comorbidity and TreatmentR00AA029459 · NIAAA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Marilyn Piccirillo · 2024 to 2026
$727k
Longitudinal Risk Factors For Depression and Development of Individual Risk ModelsF31MH115641 · NIMH · WASHINGTON UNIVERSITY · PI PICCIRILLO, MARILYN · 2017 to 2018
$74k
NIAAA NIH HHS R00 AA029459NIAAA NIH HHS T32 AA007455NIMH NIH HHS F31 MH115641
6 · The paper itself

Abstract

introductionSocial anxiety disorder (SAD) and major depressive disorder (MDD) often co-occur; however, there is limited research evaluating how cognitive-affective and behavioral factors maintain SAD and MDD for specific individuals. Evidence suggests that individuals exhibit symptom-level heterogeneity, necessitating a person-specific approach to assessment and intervention. We compared group and person-specific models of SAD-MDD comorbidity and hypothesized that individuals would demonstrate person-specific patterns of comorbidity factors that differed from the group.

methodsCisgender women (N = 35) with SAD and a current or past major depressive episode were recruited. Ages ranged from 18 to 37 years old and a majority of women were White (n = 18; 51.43%). Brief ecological momentary assessment surveys related to SAD-MDD comorbidity were administered five times a day for a month (T = 4,357).

resultsMultilevel and person-specific network analyses were used to examine between-, within-, and person-specific patterns. Intra-daily depressed mood demonstrated the strongest connections to other variables and exhibited additional, unexpected temporal effects. All models demonstrated person-specific patterns relevant to SAD-MDD comorbidity. LIMITATIONS: These results are descriptive in nature from women with a similar psychiatric profile. Future research integrating intensive EMA and personalized modeling within the context of experimental design is needed to determine the extent to which individuals truly differ from the group.

conclusionsPatterns of SAD-MDD comorbidity varied substantially across women, underscoring the potential for results from person-specific (idiographic) networks to inform the development and implementation of personalized directives for clinical assessment and intervention.

Indexed as

Major Depressive DisorderPhobia, SocialAdolescentAdultAnxietyComorbidityDepressionFemaleHumansSurveys and QuestionnairesYoung AdultComorbidityDepressionNetwork analysesPerson-specific modelsSocial anxiety disorder

Identifiers

PMID34699851
PMCPMC8690310

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.