Evidence map›Paper›PMID 34699740›Full record

ArticleAmerican journal of ophthalmology2022

Repeatability of the Accommodative Response Measured by the Grand Seiko Autorefractor in Children With and Without Amblyopia and Adults.

Ryan N Chinn, Aparna Raghuram, Molly K Curtiss, Alyssa M Gehring, Ana Juric De Paula, Tawna L Roberts

Open access · greenAbstract read
In one paragraph

Article in American journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. The QuickSee autorefractor reliably measures the accommodative response in children compared with the Shin-Nippon autorefractor.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  3. The repeatability of accommodative accuracy in childhood unilateral amblyopia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  4. Deficits of the "Good" Eye in Amblyopia: Processing Geometric Properties.Investigative ophthalmology & visual science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ryan N ChinnDepartment of Ophthalmology, Boston Children's Hospital/Harvard Medical School, Boston, Massachusettes (R.N.C., A.R.).
Aparna RaghuramDepartment of Ophthalmology, Boston Children's Hospital/Harvard Medical School, Boston, Massachusettes (R.N.C., A.R.).
Molly K CurtissAkron Children's Hospital, Akron, Ohio (M.C., A.G., A.J.D.P., T.L.R.).
Alyssa M GehringAkron Children's Hospital, Akron, Ohio (M.C., A.G., A.J.D.P., T.L.R.).
Ana Juric De PaulaAkron Children's Hospital, Akron, Ohio (M.C., A.G., A.J.D.P., T.L.R.).
Tawna L RobertsAkron Children's Hospital, Akron, Ohio (M.C., A.G., A.J.D.P., T.L.R.); Spencer Center for Vision Research, Byers Eye Institute at Stanford University, Palo Alto, California (T.L.R.). Electronic address: tawnar@stanford.edu.
Akron Children's Hospital · USBoston Children's Hospital · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Afferent and Efferent Visual Systems During Abnormal Vision DevelopmentR01EY029307 · NEI · STANFORD UNIVERSITY · PI ROBERTS, TAWNA · 2020 to 2024
$3.0M
NEI NIH HHS P30 EY026877NEI NIH HHS R01 EY029307
6 · The paper itself

Abstract

purposeTo assess test-retest repeatability of the accommodative response (AR) in children with and without amblyopia and adults using the Grand Seiko autorefractor.

designProspective reliability assessment.

methodsTest-retest of accommodation was obtained while participants viewed 20/150 sized letters at 33 cm using the Grand Seiko autorefractor in children 5 to <11 years with amblyopia (n=24) and without amblyopia (n=36), and adults 18 to <35 years (n=34). Bland-Altman 95% limits of agreement (LOA) and intraclass correlation coefficients (ICCs) were used to assess repeatability and reliability. The AR between the fellow and amblyopic eyes of children with amblyopia and eye 1 and eye 2 of the visually normal participants was assessed using group comparisons.

resultsThe 95% LOA of the AR was greatest in the amblyopic eyes (-1.25 diopters [D], 1.62 D) of children with amblyopia. The 95% LOA were similar between the fellow eyes (-0.88 D, 0.74 D) of children with amblyopia and both eyes of the children without amblyopia (eye 1: -0.68 D, 0.71 D; eye 2: -0.59 D, 0.70 D) and the adults (eye 1: 95% LOA = -0.49 D, 0.45 D; eye 2: LOA = -0.66 D, 0.67 D). ICCs revealed the Grand Seiko autorefractor as a reliable instrument for measuring AR.

conclusionsThe Grand Seiko autorefractor was more repeatable and reliable when measuring the AR in children and adults without amblyopia than in the amblyopic eye in children with amblyopia. It is recommended that multiple measures of the AR be obtained in amblyopic eyes to improve the precision of measures.

Indexed as

AmblyopiaAccommodation, OcularAdultChildEyeHumansProspective StudiesReproducibility of Results

Identifiers

PMID34699740
PMCPMC9730550
OpenAlexW3210683121

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.