Evidence map›Paper›PMID 34699670›Full record

ArticleJournal of applied clinical medical physics2021

A novel CRT-IMRT-combined (Co-CRIM) planning technique for peripheral lung stereotactic body radiotherapy in pinnacle treatment planning system.

YanHua Duan, LiJun Zhou, Hao Wang, Hua Chen, HengLe Gu, Yan Shao, AiHui Feng, Ying Huang, XiaoLong Fu, Ning Jeff Yue and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

YanHua DuanDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
LiJun ZhouDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Hao WangDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Hua ChenDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
HengLe GuDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Yan ShaoDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
AiHui FengDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Ying HuangDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
XiaoLong FuDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Ning Jeff YueDepartment of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers University, New Jersey, USA.
Kui MaClinical helpdesk, Varian Medical Systems, Beijing, China.
Qing KongInstitute of Modern Physics, Fudan University, Shanghai, China.
ZhiYong XuDepartment of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Shanghai Chest Hospital · CNShanghai Jiao Tong University · CNFudan University Shanghai Cancer Center · CNInstitute of Modern Physics · CNRutgers, The State University of New Jersey · USVarian Medical Systems (United States) · US

Funding

Nurture projects for basic research of Shanghai Chest Hospital 2019YNJCM05Shanghai Chest Hospital 2019YNJCM05
6 · The paper itself

Abstract

objectivesThis study attempts to explore a novel peripheral lung stereotactic body radiotherapy (SBRT) planning technique that can balance the pros and cons of three-dimensional conformal radiotherapy (CRT) and intensity-modulated radiation therapy (IMRT) / volumetric modulated arc therapy (VMAT).

methodsTreatment plans were retrospectively designed based on CRT, IMRT, VMAT, and the proposed CRT-IMRT-combined (Co-CRIM) techniques using Pinnacle treatment planning system (TPS) for 20 peripheral lung cancer patients. Co-CRIM used an inverse optimization algorithm available in Pinnacle TPS. To develop a Co-CRIM plan, the number of segments in each field was limited to one, the minimum segment area was set to the internal target volume (ITV), and the minimum monitor units (MU) of the segment was the quotient of fractional dose divided by twice the number of total fields. The performance of Co-CRIM was then compared with other techniques.

resultsFor conformity index (CI), Co-CRIM performed comparably to IMRT/VMAT but better than CRT. For gradient index (GI), Co-CRIM was similar to IMRT/VMAT or CRT. For heterogeneity index (HI), Co-CRIM was comparable to IMRT/VMAT, higher than CRT. The dosimetric results of spinal cord and lung with Co-CRIM were better than CRT, comparable to IMRT, but inferior to VMAT. The MU resulted from Co-CRIM was lower than IMRT/VMAT but higher than CRT. For plan verification γ passing rate, Co-CRIM was higher than IMRT/VMAT, comparable to CRT. For planning time, Co-CRIM was shorter than CRT or VMAT but similar to IMRT.

conclusionsThe proposed Co-CRIM technique on Pinnacle TPS is an effective planning technique for peripheral lung SBRT.

Indexed as

RadiosurgeryRadiotherapy, ConformalRadiotherapy, Intensity-ModulatedHumansLungPlanning TechniquesRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective StudiesCo-CRIMCRTIMRTlung SBRTplanning strategyVMAT

Identifiers

PMID34699670
PMCPMC8664147
OpenAlexW3209254586

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.