ReviewThe American journal of case reports2021
Anorectal Mucosal Melanoma: A Case Report and Literature Review.
Review in The American journal of case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Early diagnosis and delayed treatment of anorectal melanoma in a 19-year-old female: A case report.International journal of surgery case reports · 2025Article
- Article
- Primary anorectal amelanotic melanoma with liver, lungs and lymph nodal metastases.BMJ case reports · 2023Article
- Anorectal Melanoma: A Case Report.Cureus · 2023Article
- Early-Stage Primary Rectal Melanoma: A Case Report.Cureus · 2023Article
- Challenges in managing anorectal melanoma, a rare malignancy.International journal of surgery case reports · 2023Article
- Organ preservation in anorectal melanoma: A tempting challenge-a case report.SAGE open medical case reports · 2023Article
- Extensive resection improves overall and disease-specific survival in localized anorectal melanoma: A SEER-based study.Frontiers in surgery · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Anorectal mucosal melanoma (AMM) is a rare and aggressive neoplasm, with a 5-year survival rate of 10%. Due to its rarity and nonspecific symptoms, the diagnosis is often made late. Surgical resection remains the criterion standard for treatment of anorectal melanoma. CASE REPORT We present the case of an 81-year-old woman presenting with hematochezia, anal secretion, tenesmus, difficulty in defecation, and perianal pain. On physical examination, there was a prolapse of a 5-cm melanocytic nodule in the anal canal, hard on palpation. Biopsy confirmed anorectal melanoma. Staging revealed anal and metastatic disease, with adrenal, lymphatic, and hepatic involvement. As the patient continued to have bleeding, severe pain, and difficulty in defecation, she was submitted to a wide local excision. At 5-month follow-up, the anal lesion had relapsed, and the patient died 10 months after the procedure. CONCLUSIONS AMM is a rare and extremely aggressive tumor. Symptoms are nonspecific but early diagnosis should be pursued to allow curative treatment. Surgical resection with free margins is the goal of surgical treatment. New therapies are being studied, including immunotherapy, which can improve the dismal prognosis of this rare disease.
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