Evidence map›Paper›PMID 34698975›Full record

ReviewWorld journal of microbiology & biotechnology2021

Recent progress on n-butanol production by lactic acid bacteria.

Qi Li, Jieze Zhang, Junjie Yang, Yu Jiang, Sheng Yang

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Enhanced growth of 1-butanol producingBiodesign research · 2026
    Article
  2. Article
  3. Unveiling Metabolic Engineering Strategies by Quantitative Heterologous Pathway Design.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. The potential of native and engineered Clostridia for biomass biorefining.Frontiers in bioengineering and biotechnology · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Qi LiCollege of Life Sciences, Sichuan Normal University, Chengdu, 610101, China.
Jieze ZhangDepartment of Chemistry, University of Southern California, Los Angeles, CA, 90089, USA.
Junjie YangKey Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai, 200032, China.
Yu JiangHuzhou Center of Industrial Biotechnology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Huzhou, 313000, China.
Sheng YangKey Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai, 200032, China. syang@sibs.ac.cn.ORCID http://orcid.org/0000-0003-3742-9989
Chinese Academy of Sciences · CNUniversity of Southern California · US

Funding

Applied basic research program of Science and Technology Department of Sichuan Province 2021YJ0273National Natural Science Foundation of China 21825804National Natural Science Foundation of China 31921006National Natural Science Foundation of China 31971343National Natural Science Foundation of China 32071420
6 · The paper itself

Abstract

n-Butanol is an essential chemical intermediate produced through microbial fermentation. However, its toxicity to microbial cells has limited its production to a great extent. The anaerobe lactic acid bacteria (LAB) are the most resistant to n-butanol, so it should be the first choice for improving n-butanol production. The present article aims to review the following aspects of n-butanol production by LAB: (1) the tolerance of LAB to n-butanol, including its tolerance level and potential tolerance mechanisms; (2) genome editing tools in the n-butanol-resistant LAB; (3) methods of LAB modification for n-butanol production and the production levels after modification. This review will provide a theoretical basis for further research on n-butanol production by LAB.

Indexed as

1-ButanolLactobacillalesMetabolic EngineeringAnaerobiosisButanolsFermentationGene EditingIndustrial MicrobiologyMetabolic Networks and PathwaysStress, Physiological1-ButanolButanolsAnaerobicButanolGenome editingLactic acid bacteriaMetabolic engineeringTolerance

Identifiers

PMID34698975
OpenAlexW3210239443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.