Evidence map›Paper›PMID 34698956›Full record

ReviewEmergency radiology2022

COVID-19 ARDS: a review of imaging features and overview of mechanical ventilation and its complications.

Babina Gosangi, Ami N Rubinowitz, David Irugu, Christopher Gange, Anna Bader, Isabel Cortopassi

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Emergency radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Babina GosangiDepartment of Radiology & Biomedical Imaging, Yale School of Medicine; Thoracic Imaging section, Yale-New Haven Hospital, Yale New Haven Health, New Haven, CT, USA. babina.gosangi@yale.edu.ORCID http://orcid.org/0000-0003-4855-4232
Ami N RubinowitzDepartment of Radiology & Biomedical Imaging, Yale School of Medicine; Thoracic Imaging section, Yale-New Haven Hospital, Yale New Haven Health, New Haven, CT, USA.
David IruguMagnus Hospitals, Hyderabad, India.
Christopher GangeDepartment of Radiology & Biomedical Imaging, Yale School of Medicine; Thoracic Imaging section, Yale-New Haven Hospital, Yale New Haven Health, New Haven, CT, USA.
Anna BaderDepartment of Radiology & Biomedical Imaging, Yale School of Medicine; Thoracic Imaging section, Yale-New Haven Hospital, Yale New Haven Health, New Haven, CT, USA.
Isabel CortopassiDepartment of Radiology & Biomedical Imaging, Yale School of Medicine; Thoracic Imaging section, Yale-New Haven Hospital, Yale New Haven Health, New Haven, CT, USA.
Yale New Haven Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

The first cluster of cases of COVID-19 pneumonia was reported on December 31, 2019. Since then, this disease has spread rapidly across the world, and as of September 17, 2021, there are 226,844,344 cases of COVID-19 worldwide with 4,666,334 deaths related to COVID-19. While most COVID-19 cases are mild, some cases are severe with patients developing acute respiratory distress syndrome (ARDS). The pathophysiology of ARDS includes damage to the alveolar epithelium that leads to increased permeability of the alveolar epithelial barrier causing hyaline membrane formation, interstitial edema, and alveolar edema that results in severe hypoxia. Patients with COVID-19 ARDS are supported by non-invasive or invasive mechanical ventilation with an aim to improve oxygenation and maintain adequate blood oxygen levels. Increased intra-alveolar pressure while on mechanical ventilation may lead to alveolar rupture and thus barotrauma-related injuries such as lung tension cysts, pulmonary interstitial emphysema (PIE), pneumomediastinum, pneumopericardium, and pneumothorax. Recent studies have shown that the rate of barotrauma-related events is higher in patients with COVID-19 ARDS compared to patients with ARDS secondary to other etiologies. Radiologists should be aware of the imaging features of COVID-19 ARDS as well as the complications of mechanical ventilation. This educational manuscript will review the features of COVID-19 ARDS, discuss imaging of patients on mechanical ventilation, and review the imaging features of complications related to mechanical ventilation, including ventilator-associated lung injuries.

Indexed as

COVID-19Respiratory Distress SyndromeHumansOxygen SaturationRespiration, ArtificialSARS-CoV-2Acute respiratory distress syndromeARDSComplications of mechanical ventilationCovid-19 ARDSEndotracheal intubationPneumomediastinumPneumothorax

Identifiers

PMID34698956
PMCPMC8545770
OpenAlexW3209312878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.