ArticleArchives of orthopaedic and trauma surgery2022
Use of tranexamic acid in medial open wedge high tibial osteotomy.
Article in Archives of orthopaedic and trauma surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- The Optimal Dose, Efficacy and Safety of Tranexamic Acid on Hemorrhage Control for High Tibial Osteotomy: A Network Meta-Analysis.Orthopaedic surgery · 2025Pooled it
- Does tranexamic acid diminish hemorrhage and pain in open elbow arthrolysis? a systematic review and meta-analysis.BMC musculoskeletal disorders · 2023Pooled it
- The use of tranexamic acid reduces blood loss in osteotomy at knee level: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Nineteen percent of meniscus repairs are being revised and failures frequently occur after the second postoperative year: a systematic review and meta-analysis with a minimum follow-up of 5 years.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Outcomes of early versus late functional weight-bearing after the acute Achilles tendon rupture repair with minimally invasive surgery: a randomized controlled trial.Archives of orthopaedic and trauma surgery · 2023Trial
- Medial open-wedge high tibial osteotomy demonstrates an 85.9% non-conversion rate and 76.8% patient satisfaction at a minimum follow-up of 10 years.Journal of experimental orthopaedics · 2026Article
- Evaluating the benefits of using drainage tubes after high tibial osteotomy: A retrospective study.The Journal of international medical research · 2026Article
- [Modified medial wedge osteotomy for correction of double varus deformity and increased tibial slope].Operative Orthopadie und Traumatologie · 2025Review
- [Modified pendulum osteotomy to correct severe tibial varus deformity].Operative Orthopadie und Traumatologie · 2024Article
- [Medial closing wedge osteotomy for correction of valgus deformity].Operative Orthopadie und Traumatologie · 2024Article
- [Subtuberosity anterior closing wedge osteotomy to correct the increased posterior slope of the tibial plateau].Operative Orthopadie und Traumatologie · 2024Review
- Clinical Use of Tranexamic Acid in High Tibial Osteotomy: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2024Article
- Clinical Outcomes Following Use of Tranexamic Acid in High Tibial Osteotomy: A Systematic Review.Cureus · 2023Review
- Telemedicine visits generate accurate surgical plans across orthopaedic subspecialties.Archives of orthopaedic and trauma surgery · 2022Article
- Autologous semitendinosus tendon graft could function as a meniscal transplant.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAim of this study was to evaluate the effect of tranexamic acid (TXA) on the outcome after medial open wedge osteotomy. MATERIAL AND
methodsA prospective non-randomized comparative study with 52 patients has been performed. In both treatment groups, the same surgical technique for the medial open wedge HTO was used. In group 1 (N: 26) the patients received 1 g TXA i.v. preoperatively, in group 2 (N: 26) no TXA was given. Primary outcome measure was the decrease in hemoglobin concentration. Secondary outcome criteria were postoperative pain, intraarticular effusion (measured by ultrasound), range of motion (ROM) at discharge, peri- and postoperative complications and the KOOS PS (pre- and postoperatively at 1 year follow up).
resultsHemoglobin decrease was significantly less in the TXA group compared to the non TXA group. Postoperative pain and intraarticular effusion was also significantly lower and ROM at discharge was higher in the TXA group. There was no group difference in peri- and postoperative complications and the pre- and postoperatively KOOS PS.
conclusionsThe results of the present study show the systemic application of 1 g TXA reduces hemoglobin drop and postoperative morbidity (pain, intraarticular effusion, and ROM) after tibial open wedge HTO.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.