Evidence map›Paper›PMID 34698924›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Minimal clinically important difference in postoperative recovery among patients with gastrointestinal cancer.

Tsuyoshi Hara, Eisuke Kogure, Shinno Iijima, Yasuhisa Fukawa, Akira Kubo, Wataru Kakuda

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Responsiveness and minimal clinically important difference of the 6-minute walk distance in patients undergoing colorectal cancer surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tsuyoshi HaraDepartment of Physical Therapy, School of Health Science, International University of Health and Welfare, Tochigi, Japan. hara@iuhw.ac.jp.ORCID http://orcid.org/0000-0001-9629-9892
Eisuke KogureRehabilitation Progress Center Incorporated, Tokyo, Japan.
Shinno IijimaDivision of Rehabilitation, International University of Health and Welfare Hospital, Tochigi, Japan.
Yasuhisa FukawaDivision of Rehabilitation, International University of Health and Welfare Ichikawa Hospital, Chiba, Japan.
Akira KuboDepartment of Physical Therapy, School of Health Science, International University of Health and Welfare, Tochigi, Japan.
Wataru KakudaDepartment of Rehabilitation Medicine, School of Medicine, International University of Health and Welfare, Chiba, Japan.

Funding

japan society for the promotion of science 19K19880
6 · The paper itself

Abstract

purposeThe minimal clinically important difference (MCID) based on patient-reported outcomes is the smallest outcome change sufficiently significant to influence management and is crucial to the design and interpretation of comparative effectiveness trials. The purpose of this study was to estimate the MCID for postoperative recovery metrics in gastrointestinal cancer patients.

methodsThis was a three-institutional cohort study. Participants were 219 patients scheduled for gastrointestinal cancer elective surgery. Body mass index (BMI), isometric knee extension torque (IKET), 6-min walk test (6 MWT), and Short-Form 36-Item Health Survey (SF-36) version 2 were evaluated 1-2 days prior to surgery (baseline) and 4 weeks after surgery. Patients received postoperative rehabilitative care from a physical therapist during hospitalization. The MCID used anchor-based methods. The anchor was a score on the SF-36 physical functioning subscale greater or lower than the average score of the general Japanese population.

resultsThe receiver operating curve indicated a cutoff value on the 6 MWT of -7.8 m for clinically relevant decline (area under curve [AUC] = 0.67, 95% confidence interval [CI] = 0.599-0.741) or a 1.5% change. The cutoff value on the SF-36 role-physical subscale was -34.4 for clinically relevant decline (AUC = 0.691, 95% CI = 0.621-0.761) or a 36.6% decrease. No significant correlation was found between changes in BMI, IKET, and anchor.

conclusionPlausible MCIDs are present in patients with gastrointestinal cancer. These values can assist the interpretation of clinical trials and observation of the postoperative clinical course of gastrointestinal cancer surgery.

Indexed as

Gastrointestinal NeoplasmsMinimal Clinically Important DifferenceCohort StudiesHumansPatient Reported Outcome MeasuresPostoperative PeriodTreatment OutcomeGastrointestinal cancer patientsMinimal clinical important differencePhysical functioningPostoperative recoveryRehabilitation

Identifiers

PMID34698924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.