Evidence map›Paper›PMID 34698916›Full record

ReviewCell and tissue research2022

P75 neurotrophin receptor controls subventricular zone neural stem cell migration after stroke.

Sachin S Deshpande, Subash C Malik, Pasquale Conforti, Jia-di Lin, Yu-Hsuan Chu, Suvra Nath, Franziska Greulich, Meike-Ast Dumbach, N Henriette Uhlenhaut, Christian Schachtrup

Open access · hybridAbstract readReview
In one paragraph

Review in Cell and tissue research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Differential contribution of TrkB and p75Frontiers in molecular neuroscience · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sachin S DeshpandeInstitute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Subash C MalikInstitute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Pasquale ConfortiInstitute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Jia-di LinInstitute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Yu-Hsuan ChuInstitute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Suvra NathInstitute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Franziska GreulichMolecular Endocrinology, IDC, Helmholtz Diabetes Center (HMGU) and German Center for Diabetes Research (DZD), Munich, Germany.
Meike-Ast DumbachInstitute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
N Henriette UhlenhautMolecular Endocrinology, IDC, Helmholtz Diabetes Center (HMGU) and German Center for Diabetes Research (DZD), Munich, Germany.
Christian SchachtrupInstitute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany. christian.schachtrup@anat.uni-freiburg.de.ORCID http://orcid.org/0000-0001-9851-6299
University of Freiburg · DEDeutsches Diabetes-Zentrum e.V. · DE

Funding

Deutsche Forschungsgemeinschaft 1442/8-1Deutsche Forschungsgemeinschaft 1442/9-1
6 · The paper itself

Abstract

Stroke is the leading cause of adult disability. Endogenous neural stem/progenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to the brain repair process. However, molecular mechanisms underlying CNS disease-induced SVZ NSPC-redirected migration to the lesion area are poorly understood. Here, we show that genetic depletion of the p75 neurotrophin receptor (p75

Indexed as

Neural Stem CellsStrokeAnimalsLateral VentriclesMiceNeurogenesisReceptor, Nerve Growth FactorReceptor, Nerve Growth FactorBone morphogenetic proteinCytoskeletonIschemic strokeNeurotrophin receptorStem cell migrationVascular damage

Identifiers

PMID34698916
PMCPMC8975773
OpenAlexW3209112336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.