Evidence map›Paper›PMID 34698526›Full record

ArticleThe Journal of urology2022

Distinguishing Features of the Urinary Bacterial Microbiome in Patients with Neurogenic Lower Urinary Tract Dysfunction.

Giulia Lane, Alyssa Gracely, Christine Bassis, Stephen E Greiman, Paholo Barboglio Romo, J Quentin Clemens, Priyanka Gupta, Diana O'Dell, John T Stoffel, Anne P Cameron

Open access · greenAbstract read
In one paragraph

Article in The Journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Giulia LaneDepartment of Urology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-6977-5280
Alyssa GracelyDepartment of Urology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-7958-1749
Christine BassisDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-6047-0678
Stephen E GreimanDepartment of Biology, Georgia Southern University, Statesboro, Georgia.ORCID 0000-0003-0654-8977
Paholo Barboglio RomoDepartment of Urology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-9669-4021
J Quentin ClemensDepartment of Urology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-0759-3385
Priyanka GuptaDepartment of Urology, University of Michigan, Ann Arbor, Michigan.
Diana O'DellDepartment of Urology, University of Michigan, Ann Arbor, Michigan.
John T StoffelDepartment of Urology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-5503-4940
Anne P CameronDepartment of Urology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-7405-7040
University of Michigan · USGeorgia Southern University · USGTx (United States) · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
University of Michigan UroEPI Career Development ProgramK12DK111011 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLEMENS, J. QUENTIN, SARMA, ARUNA V · 2016 to 2025
$3.6M
Uro Translational Research and Clinical Research Training (UroTRACT)T32DK007782 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEI, JOHN T · 2000 to 2019
$2.9M
Improving urinary and sexual dysfunction after prostate surgery using shared decision makingF32DK126232 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI IPPOLITO, GIULIA MARIA ROSA · 2020 to 2021
$83k
NCATS NIH HHS UL1 TR002240NIDDK NIH HHS F32 DK126232NIDDK NIH HHS K12 DK111011NIDDK NIH HHS T32 DK007782
6 · The paper itself

Abstract

purposeWe aimed to characterize the urinary microbiome of catheterizing patients with neurogenic lower urinary tract dysfunction (NLUTD) and to evaluate differences based on type of bladder management or frequency of urinary tract infections. MATERIALS AND

methodsThis is a prospective, cross-sectional study of urine samples from asymptomatic, catheterizing patients with neurogenic lower urinary tract dysfunction who used either clean intermittent catheterization or indwelling catheters. Patients without symptoms of urinary tract infection provided a catheterized urine sample for urinalysis, culture and bacterial community microbiome analysis.

resultsA total of 95 patients submitted urine for analysis, of whom 69 had sufficient sequence reads (>1,203) for microbiome analysis. Cases with low bacterial signal amplification were associated with use of vaginal estrogen, no intradetrusor botulinum toxin A use and no growth on standard urine culture. The most abundant operational taxonomic units were from the phylum Proteobacteria, classified as

conclusions

Indexed as

MicrobiotaCatheters, IndwellingCross-Sectional StudiesFemaleHumansIntermittent Urethral CatheterizationMaleMiddle AgedProspective StudiesUrinary Bladder, NeurogenicUrinary Tract InfectionsUrinebotulinum toxinsmicrobiotaneurogenictype Aurinary bladderurinary tract infectionsurine

Identifiers

PMID34698526
PMCPMC9197513
OpenAlexW3210270089

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.