Evidence map›Paper›PMID 34698405›Full record

ArticleAllergy2022

Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways.

Hananeh Aliee, Florian Massip, Cancan Qi, Maria Stella de Biase, Jos van Nijnatten, Elin T G Kersten, Nazanin Z Kermani, Basil Khuder, Judith M Vonk, Roel C H Vermeulen and 27 more

Abstract readLetter
In one paragraph

Article in Allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Article
  7. IL-33 Expression Is Lower in Current Smokers at both Transcriptomic and Protein Levels.American journal of respiratory and critical care medicine · 2023
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  16. Multiple relationships between aerosol and COVID-19: A framework for global studies.Gondwana research : international geoscience journal · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

37 authors.

Hananeh AlieeInstitute of Computational Biology, Helmholtz Centre, Munich, Germany.
Florian MassipBerlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
Cancan QiUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.ORCID 0000-0003-3825-5802
Maria Stella de BiaseBerlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
Jos van NijnattenUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Elin T G KerstenUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Nazanin Z KermaniDepartment of computing, Data Science Institute, Imperial College London, London, UK.
Basil KhuderDivision of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Judith M VonkUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Roel C H VermeulenJulius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
U-BIOPRED study group
Cambridge Lung Cancer Early Detection Programme
INER-Ciencias Mexican Lung Program
Margaret NeighborsOMNI Biomarker Development, Genentech Inc., South San Francisco, California, USA.
Gaik W TewProduct Development Immunology, Infectious Disease & Opthalmology, Genentech Inc., South San Francisco, California, USA.
Michele A GrimbaldestonOMNI Biomarker Development, Genentech Inc., South San Francisco, California, USA.
Nick H T Ten HackenDepartment of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Sile HuDepartment of statistics, University of Oxford, Oxford, UK.
Yike GuoDepartment of computing, Data Science Institute, Imperial College London, London, UK.
Xiaoyu ZhangDepartment of computing, Data Science Institute, Imperial College London, London, UK.ORCID 0000-0002-6033-0525
Kai SunDepartment of computing, Data Science Institute, Imperial College London, London, UK.
Pieter S HiemstraDepartment of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.
Bruce A PonderCancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
Mika J MäkeläDepartment of Allergy, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Kristiina MalmströmDepartment of Allergy, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Robert C RintoulDepartment of Oncology, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK.
Paul A ReyfmanDivision of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-6435-6001
Fabian J TheisInstitute of Computational Biology, Helmholtz Centre, Munich, Germany.
Corry-Anke BrandsmaUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Ian M AdcockNational Heart and Lung Institute, London, UK.
Wim TimensUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Cheng-Jian XuResearch group Bioinformatics and Computational Genomics, Centre for Individualised Infection Medicine, CiiM, Hannover Medical School, Helmholtz Centre for Infection Research, Hannover, Germany.
Maarten van den BergeUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Roland F SchwarzBerlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
Gerard H KoppelmanUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
M C NawijnUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.
Alen FaizUniversity of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands.

Funding

Single-Cell Transcriptomic Analysis to Identify Drivers of Pulmonary FibrosisK08HL146943 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI REYFMAN, PAUL A · 2020 to 2021
$326k
ATS Foundation/Boehringer Ingelheim Pharmaceuticals Inc. Research FellowshipCambridge BioresourceCambridge NIHR Biomedical Research CentreCancer Research UK Cambridge CentreChan Zuckerberg InitiativeChina Scholarship CouncilEuropean Union's H2020 Research and Innovation Program 874656European Union's Seventh Framework Programme FP7/2007-2013Helmholtz Association NIH K08HL146943Innovative Medicines Initiative Joint 115010Longfonds Junior FellowshipMedical Research Council MR/T010371/1NHLBI NIH HHS K08 HL146943Parker B. Francis FellowshipThe Netherlands Lung Foundation AF 4.1.14.001The Netherlands Ministry of Health, Welfare, and SportThe Netherlands Ministry of Spatial Planning, Housing, and the EnvironmentThe Netherlands Organization for Health Research and DevelopmentThe Netherlands Organization for Scientific Research
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19SARS-CoV-2HumansRespiratory SystemSerine EndopeptidasesSerine Endopeptidases

Identifiers

PMID34698405
PMCPMC8652715

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.