Evidence map›Paper›PMID 34698211›Full record

ArticleJournal of developmental biology2021

Loss of the Extracellular Matrix Protein DIG-1 Causes Glial Fragmentation, Dendrite Breakage, and Dendrite Extension Defects.

Megan K Chong, Elizabeth R Cebul, Karolina Mizeracka, Maxwell G Heiman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Glia Development and Function in the NematodeCold Spring Harbor perspectives in biology · 2024
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Megan K ChongDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-4271-4365
Elizabeth R CebulDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-5218-265X
Karolina MizerackaDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Maxwell G HeimanDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-2557-6490
Boston Children's Hospital · US

Funding

Development of Specific Neuron-Glia AttachmentsR01NS112343 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI Maxwell Heiman · 2019 to 2026
$3.3M
ZP Domain Proteins and Epithelial IntegrityR01GM108754 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI HEIMAN, MAXWELL · 2014 to 2018
$1.7M
Formation of a neuron-glia contact at single-cell resolution in C. elegansF31NS103371 · NINDS · HARVARD MEDICAL SCHOOL · PI CEBUL, ELIZABETH ROSE · 2017 to 2018
$64k
NIGMS NIH HHS R01 GM108754NIH HHS F31NS103371NIH HHS R01GM108754NIH HHS R01NS112343NINDS NIH HHS F31 NS103371NINDS NIH HHS R01 NS112343
6 · The paper itself

Abstract

The extracellular matrix (ECM) guides and constrains the shape of the nervous system. In

Indexed as

C. elegansdendritesDIG-1extracellular matrixglianeurodevelopment

Identifiers

PMID34698211
PMCPMC8544517
OpenAlexW3201760514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.