Evidence map›Paper›PMID 34698192›Full record

ArticleGels (Basel, Switzerland)2021

3D Printed Chitosan-Pectin Hydrogels: From Rheological Characterization to Scaffold Development and Assessment.

Iratxe Zarandona, Carlos Bengoechea, Estefanía Álvarez-Castillo, Koro de la Caba, Antonio Guerrero, Pedro Guerrero

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  3. Pectin hydrogels for controlled drug release: Recent developments and future prospects.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Iratxe ZarandonaBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.
Carlos BengoecheaDepartamento de Ingeniería Química, Universidad de Sevilla, Escuela Politécnica Superior, Calle Virgen de África, 7, 41011 Sevilla, Spain.ORCID 0000-0002-4794-731X
Estefanía Álvarez-CastilloDepartamento de Ingeniería Química, Universidad de Sevilla, Escuela Politécnica Superior, Calle Virgen de África, 7, 41011 Sevilla, Spain.ORCID 0000-0002-2576-6585
Koro de la CabaBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-8866-7314
Antonio GuerreroDepartamento de Ingeniería Química, Universidad de Sevilla, Escuela Politécnica Superior, Calle Virgen de África, 7, 41011 Sevilla, Spain.ORCID 0000-0001-6050-8699
Pedro GuerreroBIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-9785-7048
Universidad de Sevilla · ESUniversity of the Basque Country · ES

Funding

MCI/AEI/FEDER, UE RTI2018-097100-B-C21 and RTI2018-097100-B-C22
6 · The paper itself

Abstract

Chitosan-pectin hydrogels were prepared, and their rheological properties were assessed in order to select the best system to develop scaffolds by 3D printing. Hydrogels showed a weak gel behavior with shear thinning flow properties, caused by the physical interactions formed between both polysaccharides, as observed by FTIR analysis. Since systems with high concentration of pectin showed aggregations, the system composed of 2 wt% chitosan and 2 wt% pectin (CHI2PEC2) was selected for 3D printing. 3D printed scaffolds showed good shape accuracy, and SEM and XRD analyses revealed a homogeneous and amorphous structure. Moreover, scaffolds were stable and kept their shape and size after a cycle of compression sweeps. Their integrity was also maintained after immersion in PBS at 37 °C, showing a high swelling capacity, suitable for exudate absorption in wound healing applications.

Indexed as

3D printingchitosanpectinrheologyscaffolds

Identifiers

PMID34698192
PMCPMC8544460
OpenAlexW3207256173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.