Evidence map›Paper›PMID 34698143›Full record

ReviewDiseases (Basel, Switzerland)2021

COVID-19 Associated Mucormycosis: A Systematic Review from Diagnostic Challenges to Management.

Farah Yasmin, Hala Najeeb, Aisha Naeem, Kartik Dapke, Rachana Phadke, Muhammad Sohaib Asghar, Syed Muhammad Ismail Shah, Domenico De Berardis, Irfan Ullah

Open access · goldAbstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Post-COVID-19 Jaw Osteonecrosis: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Focusing COVID-19-associated mucormycosis: a major threat to immunocompromised COVID-19.Environmental science and pollution research international · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. COVID-19-Associated Pulmonary Mucormycosis.Journal of fungi (Basel, Switzerland) · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Farah YasminDepartment of Internal Medicine, Dow University of Health Sciences, Karachi 74200, Pakistan.
Hala NajeebDepartment of Internal Medicine, Dow University of Health Sciences, Karachi 74200, Pakistan.
Aisha NaeemDepartment of Internal Medicine, Dow University of Health Sciences, Karachi 74200, Pakistan.
Kartik DapkeIndira Gandhi Government Medical College, Nagpur 440018, India.ORCID 0000-0003-4571-3453
Rachana PhadkeIndira Gandhi Government Medical College, Nagpur 440018, India.
Muhammad Sohaib AsgharDepartment of Internal Medicine, Dow University Ojha Hospital, Karachi 74233, Pakistan.ORCID 0000-0001-6705-2030
Syed Muhammad Ismail ShahDepartment of Internal Medicine, Ziauddin Medical University, Karachi 75600, Pakistan.
Domenico De BerardisNHS, Department of Mental Health, Psychiatric Service for Diagnosis and Treatment, Hospital "G. Mazzini", ASL 4, 64100 Teramo, Italy.ORCID 0000-0003-4415-5058
Irfan UllahDepartment of Internal Medicine, Kabir Medical College, Gandhara University, Peshawar 25000, Pakistan.ORCID 0000-0003-1100-101X
Dow University of Health Sciences · PKGovernment Medical College · INGandhara University · PKZiauddin University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) outbreak has caused significant destruction, claiming over three million lives worldwide. Post SARS-COV-2 invasion, immunosuppression with hyperglycemia and elevated ferritin levels along with steroidal treatment creates a perfect storm for opportunistic infections. There is increasing evidence of mucormycosis co-infection in COVID-19 patients, during or post-treatment. A worse prognosis, a late diagnosis, and limited guidelines of screening and management of COVID-19 associated mucormycosis have made healthcare professionals fear an epidemic alongside a pandemic. This review geographically reports cases of COVID-19 associated mucormycosis (CAM), evaluates characteristics, clinical manifestations, and outcomes of mucormycosis in COVID-19 active or recovered patients. It further describes preventive strategies and recommendations for optimal management therapy that can be adopted worldwide to curtail an impending threat to the healthcare system.

Indexed as

black fungusCOVID-19 associated Mucormycosis (CAM)hyperglycemiamucormycosissevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Identifiers

PMID34698143
PMCPMC8544552
OpenAlexW3200266136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.