Evidence map›Paper›PMID 34698142›Full record

ReviewDermatopathology (Basel, Switzerland)2021

Venous Malformations in Childhood: Clinical, Histopathological and Genetics Update.

Isabel Colmenero, Nicole Knöpfel

Abstract readReview
In one paragraph

Review in Dermatopathology (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Constitutive, Mosaic Expression of TIE2 p.L914F During Mouse Development Causes Venous Malformation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Article
  3. Vascular Vexation: The Diagnostic Journey of an Adolescent Tongue Swelling.International journal of clinical pediatric dentistry · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. New Insights in Paediatric Dermatopathology-2nd Edition.Dermatopathology (Basel, Switzerland) · 2024
    Article
  14. Review
  15. Article
  16. Review
  17. New Insights in Paediatric Dermatopathology.Dermatopathology (Basel, Switzerland) · 2021
    Article
  18. Vascular Malformations.Indian dermatology online journal
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Isabel ColmeneroDepartment of Pathology, Hospital Infantil Universitario Niño Jesús, 28009 Madrid, Spain.
Nicole KnöpfelDepartment of Dermatology, Great Ormond Street Hospital for Children and UCL GOS Institute of Child Health, London WC1N 3JH, UK.ORCID 0000-0002-6438-6550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our knowledge in vascular anomalies has grown tremendously in the past decade with the identification of key molecular pathways and genetic mutations that drive the development of vascular tumors and vascular malformations. This has led us to better understand the pathogenesis of vascular lesions, refine their diagnosis and update their classification while also exploring the opportunity for a targeted molecular treatment. This paper aims to provide an overview of venous malformations (VM) in childhood. Specific entities include common VMs, cutaneo-mucosal VM, blue rubber bleb nevus syndrome or Bean syndrome, glomuvenous malformation, cerebral cavernous malformation, familial intraosseous vascular malformation and verrucous venous malformation. The clinicopathological features and the molecular basis of each entity are reviewed.

Indexed as

geneticshistopathologysomatic and germline mutationstargeted therapyvascular anomaliesvenous malformations

Identifiers

PMID34698142
PMCPMC8544485

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.