Evidence map›Paper›PMID 34698101›Full record

ArticleCurrent issues in molecular biology2021

Antidiabetic Effect of Taxifolin in Cultured L6 Myotubes and Type 2 Diabetic Model KK-A

Shinji Kondo, Shin-Ichi Adachi, Fumiaki Yoshizawa, Kazumi Yagasaki

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shinji KondoCenter for Bioscience Research and Education, Utsunomiya University, Utsunomiya 321-8505, Japan.
Shin-Ichi AdachiCenter for Bioscience Research and Education, Utsunomiya University, Utsunomiya 321-8505, Japan.
Fumiaki YoshizawaSchool of Agriculture, Utsunomiya University, Utsunomiya 321-8505, Japan.ORCID 0000-0001-8799-7701
Kazumi YagasakiCenter for Bioscience Research and Education, Utsunomiya University, Utsunomiya 321-8505, Japan.ORCID 0000-0002-9494-9887
Utsunomiya University · JP

Funding

Japan Society for the Promotion of Science 15K07424Japan Society for the Promotion of Science 16K16273Regional Innovation Strategy Support Program, MEXT, Japan No Number
6 · The paper itself

Abstract

Muscle is the largest tissue in our body and plays an important role in glucose homeostasis and hence diabetes. In the present study, we examined the effects of taxifolin (TXF) on glucose metabolism in cultured L6 muscle cells (myotubes) and in type 2 diabetic (T2D) model KK-A

Indexed as

AMP-Activated Protein KinasesAnimalsBlood GlucoseBody WeightDiabetes Mellitus, Type 2Disease Models, AnimalDose-Response Relationship, DrugGlucoseGlucose Transporter Type 4HyperglycemiaHyperuricemiaHypoglycemic AgentsLipidsMaleMiceMuscle Fibers, SkeletalAMP-Activated Protein KinasesBlood GlucoseGlucoseGlucose Transporter Type 4Hypoglycemic AgentsLipidsProto-Oncogene Proteins c-aktQuercetintaxifolinAktAMPKGLUT4hyperglycemiahyperuricemiaKK-Ay/Ta mouseL6 myotubePI3Ktaxifolintype 2 diabetes

Identifiers

PMID34698101
PMCPMC8929065
OpenAlexW3202978444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.