Evidence map›Paper›PMID 34697929›Full record

ArticleJournal of Korean medical science2021

Fracture Risk and Its Prevention Patterns in Korean Patients with Polymyalgia Rheumatica: a Retrospective Cohort Study.

Bora Nam, Yoon-Kyoung Sung, Chan-Bum Choi, Tae-Hwan Kim, Jae-Bum Jun, Sang-Cheol Bae, Dae-Hyun Yoo, Soo-Kyung Cho

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bora NamDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.ORCID https://orcid.org/0000-0003-0215-3855
Yoon-Kyoung SungDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.ORCID https://orcid.org/0000-0001-6691-8939
Chan-Bum ChoiDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.ORCID https://orcid.org/0000-0002-4691-5455
Tae-Hwan KimDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.ORCID https://orcid.org/0000-0002-3542-2276
Jae-Bum JunDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.ORCID https://orcid.org/0000-0002-0208-0505
Sang-Cheol BaeDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.ORCID https://orcid.org/0000-0003-4658-1093
Dae-Hyun YooDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.ORCID https://orcid.org/0000-0002-0643-4008
Soo-Kyung ChoDepartment of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.ORCID https://orcid.org/0000-0003-4493-8837
Hanyang University Seoul Hospital · KR

Funding

Ministry of Health and Welfare HC19C0047Ministry of Health and Welfare HI19C0481
6 · The paper itself

Abstract

backgroundTo evaluate the incidence of fractures and fracture risk factors in Korean patients with polymyalgia rheumatica (PMR).

methodsAll PMR patients who visited a rheumatology clinic at a tertiary referral hospital between March 2005 and March 2018 were retrospectively assessed. We estimated bone mineral density (BMD) screening rate within 6 months of the first visit and classified the patients according to the performance and results of BMD screening. Incidence rates (IRs) of fractures were calculated in each group and risk factors for fractures were identified using Poisson regression analysis.

resultsA total of 95 PMR patients with median (interquartile range) age of 64.0 (56.0-72.0) years were included. Baseline BMD was assessed in only 55.8% of these patients (n = 53); 24 patients with osteoporosis, 20 with osteopenia, and 9 with normal BMD. During 433.1 person-years (PYs) of observation, 17 fractures occurred in 12 patients (IR, 3.93 [95% confidence interval (CI), 2.46-6.26]/100 PYs); 8.32 (95% CI, 4.09-16.90)/100 PYs in the osteopenia group, 3.40 (95% CI, 1.30-8.90)/100 PYs in the osteoporosis group, and 3.37 (95% CI, 1.53-7.39)/100 PYs in the no BMD test group. Risk factors for fractures were female sex, advanced age (≥ 65 years), longer follow-up duration, initial glucocorticoid dose ≥ 10 mg/day, and higher cumulative glucocorticoid dose over the first 6 months.

conclusionThe incidence rate of fractures in Korean patients with PMR was 3.93/100 PYs. Female sex, advanced age, longer follow-up duration, and increased glucocorticoid dose are risk factors for osteoporotic fracture.

Indexed as

AgedAge FactorsBone DensityBone Diseases, MetabolicFemaleFractures, BoneGlucocorticoidsHumansIncidenceMaleMiddle AgedOsteoporosisPolymyalgia RheumaticaRepublic of KoreaRetrospective StudiesRisk FactorsGlucocorticoidsBone Mineral DensityFractureOsteoporosisPolymyalgia Rheumatica

Identifiers

PMID34697929
PMCPMC8546306
OpenAlexW3199737319

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.