Evidence map›Paper›PMID 34697787›Full record

ArticleIrish journal of medical science2022

COVID-19-related mortality in cancer patients in an Irish setting.

Anna Linehan, Orla Fitzpatrick, Darren Cowzer, Maeve A Hennessy, Zac L Coyne, Amy Nolan, Maeve Clarke, Roisin Ni Dhonaill, Bryan T Hennessy, Patrick G Morris and 2 more

Abstract read
In one paragraph

Article in Irish journal of medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anna LinehanDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.ORCID http://orcid.org/0000-0001-9368-0479
Orla FitzpatrickDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Darren CowzerDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Maeve A HennessyDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Zac L CoyneDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Amy NolanDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Maeve ClarkeDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Roisin Ni DhonaillDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Bryan T HennessyDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Patrick G MorrisDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Liam GroganDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.
Oscar BreathnachDepartment of Medical Oncology, Beaumont Hospital, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has impacted significantly on healthcare across the globe. It has been reported to have higher incidence and be associated with worse outcomes in patients with cancer.

aimTo examine the characteristics of patients with cancer who were diagnosed with COVID-19 and to identify factors which may predict a poorer outcome.

methodsPatients attending oncology services in Beaumont Hospital who were diagnosed with COVID-19 between March and May 2020 were included. Demographics and outcomes were determined by chart review.

resultsTwenty-seven patients were included in the study. The median age was 62; 59% were male. Ten patients (37%) died all of whom had metastatic or incurable locally advanced disease. Patients with lung cancer had a higher rate of COVID-19 and poorer outcomes. Those with a performance status (PS) ≥ 3 were more likely to die than those with PS ≤ 2. Compared to those who recovered, patients who died had a higher number of organs affected by cancer and a higher mean Palliative Prognostic Score.

conclusionPatients attending oncology services during the initial phase of the COVID-19 pandemic had an increased rate of SARS-CoV-2 infection and a higher mortality rate than the general population. Those who died had more advanced cancer as demonstrated by poorer performance status, a greater burden of metastatic disease and a higher Palliative Prognostic Score.

Indexed as

COVID-19NeoplasmsFemaleHumansIncidenceMaleMiddle AgedPandemicsSARS-CoV-2CancerChemotherapyCOVID-19MalignancyMortalitySARS CoV-2

Identifiers

PMID34697787
PMCPMC8545357

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.