Evidence map›Paper›PMID 34697739›Full record

ArticleDoklady. Biochemistry and biophysics2021

Scanning Optical Probe Nanotomography for Investigation of the Structure of Biomaterials and Cells.

O I Agapova, A E Efimov, L A Safonova, M M Bobrova, I I Agapov, S V Gautier

Abstract read
PubMed Publisher
In one paragraph

Article in Doklady. Biochemistry and biophysics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Correlative Fluorescent Scanning Probe Nanotomography Used to Study the Intracellular Distribution of Doxorubicin in MCF-7 Human Breast Adenocarcinoma Cells.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

O I AgapovaShumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russia.
A E EfimovShumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russia.
L A SafonovaShumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russia.
M M BobrovaShumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russia.
I I AgapovShumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russia. igor_agapov@mail.ru.
S V GautierShumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russia.
V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Creation of new effective bio-artificial structures for tissue engineering and regenerative medicine requires development and implementation of new technological approaches for analysis of micro- and nanostructural features of constructs based on biomaterials and their interaction with cells. A new method of three-dimensional multiparametric analysis of nanostructure, scanning optical probe nanotomography, is presented in this paper, applied to the analysis of cells and biomaterials. Correlative reconstruction of fluorescent marker distributions and nanostructure features allows quantitative evaluation of a number of parameters of three-dimensional nanomorphology of fibroblasts and human hepatocarcinoma cells Hep-G2, adhered to biodegradable scaffolds based on silk fibroin. The developed technology with use of scanning optical probe nanotomography is applicable to investigation of three-dimensional micro- and nanostructure features of biomaterials and cells of different types.

Indexed as

Biocompatible MaterialsFibroinsAnimalsFibroblastsHep G2 CellsHumansTissue EngineeringTissue ScaffoldsBiocompatible MaterialsFibroinsbiocompatible scaffoldsfibroblastsfluorescence microscopyhuman hepatocarcinoma Hep-G2 cellsscanning probe nanotomographysilk fibroin

Identifiers

PMID34697739
OpenAlexW3211149260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.