Evidence map›Paper›PMID 34697592›Full record

ArticleJournal of diabetes research2021

The Role of Mesenchymal Stem Cells with Ascorbic Acid and N-Acetylcysteine on TNF-

Dalia Abdelhafez, Elshimaa Aboelkomsan, Abir El Sadik, Noha Lasheen, Sara Ashur, Amal Elshimy, George N B Morcos

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Dalia AbdelhafezDepartment of Pathology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Elshimaa AboelkomsanDepartment of Pathology, Faculty of Medicine, New Giza University, Cairo, Egypt.
Abir El SadikDepartment of Anatomy and Histology, College of Medicine, Qassim University, Saudi Arabia and Department of Anatomy and Embryology, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID https://orcid.org/0000-0003-2098-2155
Noha LasheenDepartment of Physiology, Faculty of Medicine, Ain Shams and Galala Universities, Cairo, Egypt.
Sara AshurDepartment of Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Amal ElshimyDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Cairo University, Cairo, Egypt.
George N B MorcosDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, and Department of Basic Medical Science, Faculty of Medicine, King Salman International University, Cairo, Egypt.
Cairo University · EGAin Shams University · EGFayoum University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute pancreatitis (SAP) is a necrotic pancreatic inflammation associated with high mortality rate (up to 70%). Bone marrow (BM) mesenchymal stem cells (MSCs) have been investigated in pancreatic cellular regeneration, but still their effects are controversial. Therefore, the present study is aimed at examining the enrichment of the stem cells with ascorbic acid (AA) and N-acetylcysteine (NAC) and explore their combined action on the expression of the inflammatory cytokines: interleukin 1

Indexed as

Mesenchymal Stem Cell TransplantationAcetylcysteineAnimalsAntioxidantsAscorbic AcidBlood GlucoseBody WeightCaspase 3Cell ProliferationCeruletideFluorescent DyesInsulinInterleukin-1betaIslets of LangerhansMesenchymal Stem CellsNF-kappa BAcetylcysteineAntioxidantsAscorbic AcidBlood GlucoseCaspase 3CeruletideFluorescent DyesIL1B protein, ratInsulinInterleukin-1betaNF-kappa BOrganic ChemicalsPKH 26Proliferating Cell Nuclear AntigenTumor Necrosis Factor-alpha

Identifiers

PMID34697592
PMCPMC8541853
OpenAlexW3206342895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.