Evidence map›Paper›PMID 34697591›Full record

ArticleBioMed research international2021

A Wavelet-Based Learning Model Enhances Molecular Prognosis in Pancreatic Adenocarcinoma.

Binhua Tang, Yu Chen, Yuqi Wang, Jiafei Nie

Abstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Binhua TangEpigenetics & Function Group, Hohai University, Jiangsu 213022, China.ORCID https://orcid.org/0000-0003-4744-5835
Yu ChenEpigenetics & Function Group, Hohai University, Jiangsu 213022, China.
Yuqi WangEpigenetics & Function Group, Hohai University, Jiangsu 213022, China.
Jiafei NieEpigenetics & Function Group, Hohai University, Jiangsu 213022, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide omics technology boosts deep interrogation into the clinical prognosis and inherent mechanism of pancreatic oncology. Classic LASSO methods coequally treat all candidates, ignoring individual characteristics, thus frequently deteriorating performance with comparatively more predictors. Here, we propose a wavelet-based deep learning method in variable selection and prognosis formulation for PAAD with small samples and multisource information. With the genomic, epigenomic, and clinical cohort information from The Cancer Genome Atlas, the constructed five-molecule model is validated via Kaplan-Meier survival estimate, rendering significant prognosis capability on high- and low-risk subcohorts (

Indexed as

Deep LearningWavelet AnalysisAdultAgedAged, 80 and overBiomarkers, TumorComputational BiologyDatabases, GeneticDNA MethylationFemaleHumansMaleMiddle AgedPancreatic NeoplasmsPrognosisSurvival RateBiomarkers, Tumor

Identifiers

PMID34697591
PMCPMC8541860

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.