Evidence map›Paper›PMID 34697335›Full record

ArticleScientific reports2021

Trends of new-onset psychosis or mania in psychiatric emergency departments during the COVID19 pandemic: a longitudinal comparative study.

Aviv Segev, Efrat Hirsch-Klein, Gershon Kotz, Shiri Kamhi-Nesher, Shikma Halimi, Khalil Qashu, Ephraim Schreiber, Amir Krivoy

Open access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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  9. COVID-19 associated psychosis.Industrial psychiatry journal
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Aviv Segev *Shalvata Mental Health Center, Alyat Hanoar 13th St., Hod Hasharon, Israel. Segev_a@netvision.net.il.
Efrat Hirsch-Klein *Shalvata Mental Health Center, Alyat Hanoar 13th St., Hod Hasharon, Israel.
Gershon KotzSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Shiri Kamhi-NesherSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Shikma HalimiSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Khalil QashuShalvata Mental Health Center, Alyat Hanoar 13th St., Hod Hasharon, Israel.
Ephraim SchreiberShalvata Mental Health Center, Alyat Hanoar 13th St., Hod Hasharon, Israel.
Amir KrivoySackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv University · ILShalvata Mental Health Center · ILGeha Mental Health Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID19 infection was associated with possible psychiatric manifestations, including psychosis and mania. In addition, psychiatric disorders might be triggered by severe psychological reactions to the pandemic or the measures taken to contain it. This study aimed to assess the trends of new-onset psychosis/mania during the pandemic timeline. Psychiatric emergency department records during January-July 2019 and 2020 of two regional mental health centers were manually examined. Cases of new-onset psychosis or mania were found in 326 out of 5161 records examined. The ratio of these cases increased by 45.5% in 2020 compared to 2019 (189 out of 2367, 137 out of 2479, respectively, p = 0.001). The peak increase was in April 2020 (9.4% vs. 4.7%, p = 0.015). There was no association between the rise of new-onset psychotic or manic episodes and national incidence of COVID19 cases, as observed during Israel 2nd wave. PCR tests were negative, except a single case. In this study, an increase in new-onset psychosis/mania was identified during the initial phase of the pandemic. Though causality could not be directly inferred, lack of infection symptoms, negative PCR testing and temporal distribution incongruent with COVID19 caseload did not support a direct effect of SARS-CoV-2. Alternative explanations are discussed, such as psychological reaction to stress and preventive measures, as well as case-shifting between different mental health settings.

Indexed as

AdolescentAdultAgedAged, 80 and overBipolar DisorderCOVID-19COVID-19 Nucleic Acid TestingElectronic Health RecordsEmergency Service, HospitalFemaleHospitals, PsychiatricHumansIsraelLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID34697335
PMCPMC8546064
OpenAlexW3210339148

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.