Evidence map›Paper›PMID 34697270›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2021

Hydrogen sulfide, a gaseous signaling molecule, elongates primary cilia on kidney tubular epithelial cells by activating extracellular signal-regulated kinase.

Sang Jun Han, Jee In Kim, Joshua H Lipschutz, Kwon Moo Park

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Sulfide is a keystone metabolite for gut homeostasis and immunity.bioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Sang Jun HanDepartment of Biotechnology, College of Fisheries Sciences, Pukyong National University, Busan 48513, Korea.
Jee In KimDepartment of Molecular Medicine, Keimyung University School of Medicine, Daegu 42601, Korea.
Joshua H LipschutzDepartment of Medicine, Medical University of South Carolina, SC 29425, USA.
Kwon Moo ParkDepartment of Anatomy, BK21 Plus, Cardiovascular Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Keimyung University · KRKyungpook National University · KRMedical University of South Carolina · USPukyong National University · KR

Funding

The exocyst in ciliogenesis and cystogenesisI01BX000820 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI JOSHUA H LIPSCHUTZ · 2011 to 2026
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BLRD VA I01 BX000820
6 · The paper itself

Abstract

Primary cilia on kidney tubular cells play crucial roles in maintaining structure and physiological function. Emerging evidence indicates that the absence of primary cilia, and their length, are associated with kidney diseases. The length of primary cilia in kidney tubular epithelial cells depends, at least in part, on oxidative stress and extracellular signal-regulated kinase 1/2 (ERK) activation. Hydrogen sulfide (H

Indexed as

CiliogenesisERKEXOC5Hydrogen sulfidePrimary ciliaSec10

Identifiers

PMID34697270
PMCPMC8552824
OpenAlexW3208466827

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.