Evidence map›Paper›PMID 34697190›Full record

ArticleIn vivo (Athens, Greece)

Visualisation of Range Shortening in Carbon Ion Beams and Washout of Positron Emitter: First-in-Human Report.

Shintaro Shiba, Makoto Sakai, Masahiko Okamoto, Tatsuya Ohno

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shintaro ShibaDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Makoto SakaiGunma University Heavy Ion Medical Center, Maebashi, Japan sakai-m@gunma-u.ac.jp.
Masahiko OkamotoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Tatsuya OhnoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Gunma University · JPGunma University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAuto-activation positron emission tomography (AAPET) is one of the most promising methods to verify beam range in carbon ion radiotherapy (C-ion RT). We aimed to confirm this for the first time in a clinical setting by performing AAPET in a patient with pancreatic cancer previously receiving coil embolisation of hepatic artery pseudoaneurysm. MATERIALS AND

methodsA 70-year-old pancreatic head cancer patient was treated with C-ion RT on a clinical dose of 4.6 Gy (RBE), followed by AAPET, to verify beam ranges in C-ion RT.

resultsPositron emission tomography (PET) revealed low positron emitter concentrations at the distal side of the internal metals and in the aorta compared to the dose distribution of the treatment plan, indicating range shortening by internal metals in C-ion beams and positron emitter transportation by biofluids.

conclusionAAPET may detect range shortening by internal metals in the trajectory and washout of intravascular positron emitter compared to plan dose distribution.

Indexed as

ElectronsHeavy Ion RadiotherapyAgedCarbonHumansPhantoms, ImagingPositron-Emission TomographyCarbonauto-activation positron emission tomographyCarbon-ion radiotherapyirradiated site visualisation

Identifiers

PMID34697190
PMCPMC8627780
OpenAlexW3211078645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.