Evidence map›Paper›PMID 34697171›Full record

ArticleIn vivo (Athens, Greece)

Association of Intrarenal Resistance Index and Systemic Atherosclerosis After Kidney Transplantation.

Philipp Köger, Stephan Engelberger, Christoph Thalhammer, Rudolf Wüthrich, Marie-Luise Valentin, Nils Kucher, Robert K Clemens

Open access · diamondAbstract read
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Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Philipp KögerVascular Practice Wil and University Zurich, Zurich, Switzerland.
Stephan EngelbergerVascular Center, Cantonal Hospital Baden, Baden, Switzerland.
Christoph ThalhammerClinic for Angiology, Cantonal Hospital Aargau, Aargau, Switzerland.
Rudolf WüthrichClinic for Nephrology, University Hospital and University Zurich, Zurich, Switzerland.
Marie-Luise ValentinClinic for Angiology, University Hospital and University Zurich, Zurich, Switzerland.
Nils KucherClinic for Angiology, University Hospital and University Zurich, Zurich, Switzerland.
Robert K ClemensVascular Center, Cantonal Hospital Baden, Baden, Switzerland; robert.clemens@gmx.net.
University Hospital of Zurich · CHKantonsspital Baden · CHKantonsspital Aarau · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPatients after kidney transplants are at risk of cardiovascular morbidity. An elevated resistance index (RI) is associated with renal graft failure, while a decreased RI can be due to a renal artery stenosis. The RI can also be measured in the carotid artery. Whether a correlation between intrarenal RI after kidney transplant in adult patients and the RI of the internal carotid artery exists is still unclear. PATIENTS AND

methodsIn this prospective cross-sectional study, RI of kidney transplants and of the internal carotid artery were measured with duplex sonography. Carotid intima-media thickness as well as the Framingham risk score and the Augmentation index, all known markers of atherosclerosis, were assessed. Correlations between the RI in Carotid artery and the RI of the kidney transplant were based on Spearmen test with the level of significance set at p<0.05.

resultsNinety-eight consecutive patients [60% male, mean age of 48.7 (±15.6)] were included. The mean interval after transplantation was 27.5 (±8.5) months and mean serum creatinine was 308 (±220.3) mmol/ml The RI of the internal carotid artery and the renal transplant were significantly correlated (p<0.05). A correlation between the RIs and the Augmentation Index was found.

conclusionThe RI of the kidney transplant is correlated with the RI of the carotid artery and to markers of general atherosclerosis. This observation may be helpful to identify patients after kidney transplant with higher risk for cardiovascular events and gain indirect information on transplant renal artery stenosis.

Indexed as

AtherosclerosisKidney TransplantationAdultCarotid Intima-Media ThicknessCross-Sectional StudiesFemaleHumansKidneyMaleProspective Studiescardiovascular risk factorsRenal transplantrenal transplant stenosisresistance index

Identifiers

PMID34697171
PMCPMC8627733
OpenAlexW3156736871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.