Evidence map›Paper›PMID 34697165›Full record

ArticleIn vivo (Athens, Greece)

Clinical Availability of Tumour Biopsy Using Diagnostic Laparoscopy for Advanced Ovarian Cancer.

Suguru Odajima, Kazu Ueda, Satoshi Hosoya, Keisuke Tomita, Sayako Kato, Yuichi Shoburu, Ayako Kawabata, Yasushi Iida, Nozomu Yanaihara, Aikou Okamoto

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Neoadjuvant Chemotherapy for Newly Diagnosed, Advanced Ovarian Cancer: ASCO Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Guideline
  2. Observational
  3. Article
  4. Article
  5. Ovarian metastases fromTranslational cancer research · 2022
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Suguru OdajimaDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Kazu UedaDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan; kazu@iuhw.ac.jp.
Satoshi HosoyaDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Keisuke TomitaDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Sayako KatoDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Yuichi ShoburuDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Ayako KawabataDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Yasushi IidaDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Nozomu YanaiharaDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Aikou OkamotoDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Jikei University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTumour biopsy using laparoscopy before neoadjuvant chemotherapy for advanced ovarian cancer has been widely accepted. However, there are few reports about its operative outcome compared to biopsy with laparotomy. We investigated the advantage of laparoscopic biopsy for advanced ovarian cancer. PATIENTS AND

methodsWe included 23 patients who underwent laparoscopy and 27 who underwent exploratory laparotomy before neoadjuvant chemotherapy between January 2012 and August 2020. We reviewed their medical records and evaluated their operative outcomes.

resultsBlood loss was significantly lower in the laparoscopy group (5 ml vs. 320 ml, p<0.05). The period until the initiation of neoadjuvant chemotherapy was significantly shorter in the laparoscopy group (12 days vs. 16 days, p<0.05). Overall survival did not differ significantly between the two groups (25.4 months vs. 24.7 months, p=0.53).

conclusionLaparoscopic tumour biopsy is useful and safe for histological diagnosis, thereby allowing for early introduction to neoadjuvant chemotherapy.

Indexed as

LaparoscopyOvarian NeoplasmsBiopsyCarcinoma, Ovarian EpithelialCytoreduction Surgical ProceduresFemaleHumansNeoadjuvant TherapyNeoplasm StagingRetrospective StudiesTreatment OutcomeAdvanced ovarian cancerdiagnostic laparoscopyinterval debulking surgerylaparoscopic surgerytumour biopsy

Identifiers

PMID34697165
PMCPMC8627755
OpenAlexW3208665951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.