Evidence map›Paper›PMID 34697157›Full record

ArticleIn vivo (Athens, Greece)

Lipiodol Deposition and Washout in Primary and Metastatic Liver Tumors After Chemoembolization.

Nariman Nezami, Johanna Maria Mijntje VAN Breugel, Menelaos Konstantinidis, Julius Chapiro, Lynn Jeanette Savic, Milena Anna Miszczuk, Irvin Rexha, Mingde Lin, Kelvin Hong, Christos Georgiades

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Nariman NezamiSection of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, U.S.A.; dr.nezami@gmail.com.
Johanna Maria Mijntje VAN BreugelDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, U.S.A.
Menelaos KonstantinidisDivision of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Julius ChapiroSection of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, U.S.A.
Lynn Jeanette SavicDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, U.S.A.
Milena Anna MiszczukDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, U.S.A.
Irvin RexhaDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, U.S.A.
Mingde LinVisage Imaging, Inc., San Diego, CA, U.S.A.
Kelvin HongDivision of Vascular and Interventional Radiology, Russel H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, U.S.A.
Christos GeorgiadesDivision of Vascular and Interventional Radiology, Russel H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, U.S.A.
Freie Universität Berlin · DEHumboldt-Universität zu Berlin · DEPublic Health Ontario · CAUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimLipiodol is the key component of conventional trans-arterial chemoembolization. Our aim was to evaluate lipiodol deposition and washout rate after conventional trans-arterial chemoembolization in intrahepatic cholangiocarcinoma and hepatic metastases originating from neuroendocrine tumors and colorectal carcinoma. PATIENTS AND

methodsThis was a retrospective analysis of 44 patients with intrahepatic cholangiocarcinoma and liver metastasis from neuroendocrine tumors or colorectal carcinoma who underwent conventional trans-arterial chemoembolization. Lipiodol volume (cm

resultsThe washout rate was longer for neuroendocrine tumors compared to colorectal carcinoma, with half-lives of 54.61 days (p<0.00001) and 19.39 days (p<0.001), respectively, with no exponential washout among intrahepatic cholangiocarcinomas (p=0.83). The half-life for lipiodol washout was longer in tumors larger than 300 cm

conclusionLipiodol washout is a time-dependent process, and occurs faster in colorectal carcinoma tumors, tumors smaller than 300 cm

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsEthiodized OilHumansRetrospective StudiesEthiodized Oilchemoembolizationcolorectal carcinomadepositionintrahepatic cholangiocarcinomaLipiodolneuroendocrine tumors

Identifiers

PMID34697157
PMCPMC8627740
OpenAlexW3209098523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.