Evidence map›Paper›PMID 34697146›Full record

ArticleIn vivo (Athens, Greece)

Protective Effects of Crocetin on Arsenic Trioxide-induced Oxidative Stress in Human Umbilical Vein Endothelial Cells.

Chung-Lin Tsai, Chia-Wen Tsai, Wen-Shin Chang, Jiunn-Cherng Lin, Liang-Chun Shih, Jie-Long He, DA-Tian Bau

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chung-Lin TsaiGraduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, R.O.C.
Chia-Wen TsaiGraduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, R.O.C.
Wen-Shin ChangGraduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, R.O.C.
Jiunn-Cherng LinDivision of Cardiology, Department of Internal Medicine, Taichung Veterans General Hospital Chiayi Branch, Chiayi, Taiwan, R.O.C.
Liang-Chun ShihGraduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, R.O.C.
Jie-Long HeDepartment of Post-Baccalaureate Veterinary Medicine, Asia University, Taichung, Taiwan, R.O.C.
DA-Tian BauGraduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, R.O.C.; datian@mail.cmuh.org.tw artbau2@gmail.com.
China Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe clinical use of arsenic trioxide (As MATERIALS AND

methodsCultured human umbilical vein endothelial cells (HUVECs) were used to examine As

resultsAs

conclusionCrocetin protects from As

Indexed as

ArsenicalsApoptosisArsenic TrioxideCarotenoidsHumansHuman Umbilical Vein Endothelial CellsOxidative StressOxidesReactive Oxygen SpeciesVitamin AArsenicalsArsenic TrioxideCarotenoidsOxidesReactive Oxygen Speciestrans-sodium crocetinateVitamin AApoptosisarsenic trioxidecrocetinhuman umbilical vein endothelial cellsoxidative adductsoxidative damagereactive oxygen species

Identifiers

PMID34697146
PMCPMC8627775
OpenAlexW3208941494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.